Abstract
The effect of hydrocortisone on blood CFU-C has been studied in six normal subjects through a double layer agar culture system. Increased numbers of CFU-C appeared in the peripheral blood reaching a maximum 366% to 631% increase 5-8 hours after the i.v. administration of the hormone. Contemporary lymphopenia caused a 4 to 10 fold enrichment in the proportion of CFU-C to lymphocytes. Hydrocortisone added in vitro somewhat inhibited the colony growth. The results suggest that the increase of blood CFU-C is due to mobilization from the bone marrow. Hydrocortisone, when compared to other agents, appears to offer some advantages in increasing the blood CFU-C for clinical purposes.
| Original language | English |
|---|---|
| Pages (from-to) | 87-90 |
| Number of pages | 4 |
| Journal | Biomedicine Express |
| Volume | 35 |
| Issue number | 3 |
| Publication status | Published - 1981 |
ASJC Scopus subject areas
- Medicine(all)