Mobilization of peripheral blood progenitor cells with G-CSF alone in lymphoma patients: Steady-state circulating progenitor cell count predicts the autograft yield

S. Grimaz, D. Damiani, M. Michieli, M. Baccarani

Research output: Contribution to journalArticle

Abstract

Nowadays the first choice procedure to collect hematopoietic progenitor cells for autografts is the harvest of peripheral blood progenitor cells (PBPC) mobilized with cytokines, associated or not with chemotherapy. A large amount of data is available on factors affecting mobilization, such as sex, age, number of previous chemotherapy regimens, radiotherapy, and exposure to fludarabine. The individual response to mobilization is, however, highly variable from patient to patient and only a few studies have investigated biological parameters that could predict successful mobilization of P BPC for a single patient when a given regimen is employed. Findings of this study show that when G-CSF is used as a single mobilizing agent, the baseline PBPC has a predictive value.

Original languageEnglish
Pages (from-to)102-103
Number of pages2
JournalHaematologica
Volume85
Issue number1
Publication statusPublished - 2000

Keywords

  • G-CSF
  • Mobilization
  • PBSC transplantation
  • Steady state CD34 cells

ASJC Scopus subject areas

  • Hematology

Fingerprint Dive into the research topics of 'Mobilization of peripheral blood progenitor cells with G-CSF alone in lymphoma patients: Steady-state circulating progenitor cell count predicts the autograft yield'. Together they form a unique fingerprint.

  • Cite this