Model for End-Stage Liver Disease (MELD) System to Allocate and to Share Livers: Experience of Two Italian Centers

M. Ravaioli, M. Masetti, A. Dazzi, A. Romano, M. Spaggiari, G. L. Grazi, G. Ercolani, M. Cescon, P. Di Gioia, N. De Ruvo, R. Montalti, R. Ballarin, F. Di Benedetto, L. Ridolfi, N. Alvaro, G. Ramacciato, C. Morelli, E. Gerunda, A. D. Pinna

Research output: Contribution to journalArticle

Abstract

Background: The use of the Model for End-stage Liver Disease (MELD) score to prioritize patients on liver waiting lists and to share organs among centers was effective according to US data, but few reports are available in Europe. Materials and methods: We evaluated the outcome of 887 patients listed between April 2004 and July 2006 in a common list by two transplant centers (University of Bologna [BO] and University of Modena [MO] ordered according to the MELD system. Patients with hepatocellular carcinoma had a score calculated according to their real MELD, tumor stage, and waiting time. Results: Five hundred eighty-six (67%) patients were listed from BO and 291 (33%) from MO. The clinical features of recipients (sex, age, blood group, and real MELD) were comparable between centers. The number of liver transplantations performed was 307, and 273 (89%) recipients had a calculated MELD ≥20. Liver transplantations were equally distributed according to the number of patients listed: 215 out of 586 (36.7%) for BO and 92 out of 291 (31.6%) for MO. The median real MELD of patients transplanted was 20, and 246 out of 307 (80.1%) grafts transplanted were functioning. The dropouts from the list were 124 (14%), and 87 (70%) of these patients had a calculated MELD ≥20. Conclusion: The MELD system was effective to share livers among the two Italian centers. According to this policy, livers were allocated to the recipients with the highest probability of dropout and who had a satisfactory survival after liver transplantation.

Original languageEnglish
Pages (from-to)1814-1815
Number of pages2
JournalTransplantation Proceedings
Volume40
Issue number6
DOIs
Publication statusPublished - Jul 2008

    Fingerprint

ASJC Scopus subject areas

  • Surgery
  • Transplantation

Cite this

Ravaioli, M., Masetti, M., Dazzi, A., Romano, A., Spaggiari, M., Grazi, G. L., Ercolani, G., Cescon, M., Di Gioia, P., De Ruvo, N., Montalti, R., Ballarin, R., Di Benedetto, F., Ridolfi, L., Alvaro, N., Ramacciato, G., Morelli, C., Gerunda, E., & Pinna, A. D. (2008). Model for End-Stage Liver Disease (MELD) System to Allocate and to Share Livers: Experience of Two Italian Centers. Transplantation Proceedings, 40(6), 1814-1815. https://doi.org/10.1016/j.transproceed.2008.05.053