Modeling Radiotherapy Induced Normal Tissue Complications: An Overview beyond Phenomenological Models

Marco D'Andrea; Marcello Benassi; Lidia Strigari

doi:10.1155/2016/2796186

Modeling Radiotherapy Induced Normal Tissue Complications: An Overview beyond Phenomenological Models

Marco D'Andrea, Marcello Benassi, Lidia Strigari

Istituto Regina Elena

Research output: Contribution to journal › Review article

Abstract

An overview of radiotherapy (RT) induced normal tissue complication probability (NTCP) models is presented. NTCP models based on empirical and mechanistic approaches that describe a specific radiation induced late effect proposed over time for conventional RT are reviewed with particular emphasis on their basic assumptions and related mathematical translation and their weak and strong points.

Original language	English
Article number	2796186
Journal	Computational and Mathematical Methods in Medicine
Volume	2016
DOIs	https://doi.org/10.1155/2016/2796186
Publication status	Published - 2016

ASJC Scopus subject areas

Medicine(all)
Modelling and Simulation
Immunology and Microbiology(all)
Biochemistry, Genetics and Molecular Biology(all)
Applied Mathematics

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D'Andrea, M., Benassi, M., & Strigari, L. (2016). Modeling Radiotherapy Induced Normal Tissue Complications: An Overview beyond Phenomenological Models. Computational and Mathematical Methods in Medicine, 2016, [2796186]. https://doi.org/10.1155/2016/2796186

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