Modeling Radiotherapy Induced Normal Tissue Complications: An Overview beyond Phenomenological Models

Marco D'Andrea; Marcello Benassi; Lidia Strigari

doi:10.1155/2016/2796186

Modeling Radiotherapy Induced Normal Tissue Complications: An Overview beyond Phenomenological Models

Marco D'Andrea, Marcello Benassi, Lidia Strigari

Istituto Regina Elena

Research output: Contribution to journal › Review article › peer-review

Abstract

An overview of radiotherapy (RT) induced normal tissue complication probability (NTCP) models is presented. NTCP models based on empirical and mechanistic approaches that describe a specific radiation induced late effect proposed over time for conventional RT are reviewed with particular emphasis on their basic assumptions and related mathematical translation and their weak and strong points.

Original language	English
Article number	2796186
Journal	Computational and Mathematical Methods in Medicine
Volume	2016
DOIs	https://doi.org/10.1155/2016/2796186
Publication status	Published - 2016

ASJC Scopus subject areas

Medicine(all)
Modelling and Simulation
Immunology and Microbiology(all)
Biochemistry, Genetics and Molecular Biology(all)
Applied Mathematics

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title = "Modeling Radiotherapy Induced Normal Tissue Complications: An Overview beyond Phenomenological Models",

abstract = "An overview of radiotherapy (RT) induced normal tissue complication probability (NTCP) models is presented. NTCP models based on empirical and mechanistic approaches that describe a specific radiation induced late effect proposed over time for conventional RT are reviewed with particular emphasis on their basic assumptions and related mathematical translation and their weak and strong points.",

author = "Marco D'Andrea and Marcello Benassi and Lidia Strigari",

year = "2016",

doi = "10.1155/2016/2796186",

language = "English",

volume = "2016",

journal = "Computational and Mathematical Methods in Medicine",

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T2 - An Overview beyond Phenomenological Models

AU - D'Andrea, Marco

AU - Benassi, Marcello

AU - Strigari, Lidia

PY - 2016

Y1 - 2016

N2 - An overview of radiotherapy (RT) induced normal tissue complication probability (NTCP) models is presented. NTCP models based on empirical and mechanistic approaches that describe a specific radiation induced late effect proposed over time for conventional RT are reviewed with particular emphasis on their basic assumptions and related mathematical translation and their weak and strong points.

AB - An overview of radiotherapy (RT) induced normal tissue complication probability (NTCP) models is presented. NTCP models based on empirical and mechanistic approaches that describe a specific radiation induced late effect proposed over time for conventional RT are reviewed with particular emphasis on their basic assumptions and related mathematical translation and their weak and strong points.

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U2 - 10.1155/2016/2796186

DO - 10.1155/2016/2796186

M3 - Review article

AN - SCOPUS:85006175166

VL - 2016

JO - Computational and Mathematical Methods in Medicine

JF - Computational and Mathematical Methods in Medicine

SN - 1748-670X

M1 - 2796186

ER -

Modeling Radiotherapy Induced Normal Tissue Complications: An Overview beyond Phenomenological Models

Abstract

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