Modeling the role of arterial windkessel in the enhancement and synchronization of low frequency vasomotor activity

Giuseppe Baselli, A. Porta, M. Pagani

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Arterial Windkessel mechanisms and arterial pressure (AP) low frequency (LF) waves were investigated by means of simple lumped models of a compliant resistant/arterial tree and of flow regulation in peripheral vascular districts (PVDs) with three types of feedback: 1) delay, 2) Van der Pol oscillator, 3) relay; all were able to actively compensate flow changes and to simulate peripheral LF vasomotion. Each PVD connected to a Windkessel compartment displayed a reduction and a disappearance of oscillations with low compliance, when the Windkessel equivalent time constant Teq fall below 2s. Two PVDs connected to the same Windkessel tended to phase opposition with a negative interference canceling their LF oscillations from AP, With a modest neural drive, cancellation was imperfect and AP waves appeared. Vasomotion, arterial compliances and neural triggers are all essential in forming LF AP variability.

Original languageEnglish
Title of host publicationComputers in Cardiology
EditorsA. Murray
Pages41-44
Number of pages4
Volume30
Publication statusPublished - 2003
EventComputers in Cardiology 2003 - Thessaloniki Chalkidiki, Greece
Duration: Sep 21 2003Sep 24 2003

Other

OtherComputers in Cardiology 2003
CountryGreece
CityThessaloniki Chalkidiki
Period9/21/039/24/03

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Software

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