Moderately Hypofractionated Helical IMRT, FDG–PET/CT-guided, for Progressive Malignant Pleural Mesothelioma in Patients With Intact Lungs

Andrei Fodor, Sara Broggi, Elena Incerti, Italo Dell'Oca, Claudio Fiorino, Ana M. Samanes Gajate, Marcella Pasetti, Mauro G. Cattaneo, Paolo Passoni, Luigi Gianolli, Riccardo Calandrino, Maria Picchio, Nadia Di Muzio

Research output: Contribution to journalArticle

Abstract

Fifty-one patients with malignant pleural mesothelioma treated with helical intensity-modulated radiation therapy in presence of intact lungs were analyzed. A positron emission tomography positive volume ≥ 473 cc was found predictive of early death. A positron emission tomography positive volume < 205 cc was associated with longer survival in stage III to IV patients treated with simultaneous integrated boost, and also with higher late pulmonary ≥ grade 2 toxicity.

Original languageEnglish
Pages (from-to)e29-e38
JournalClinical Lung Cancer
Volume20
Issue number1
DOIs
Publication statusPublished - Jan 2019

Keywords

  • Hypofractionation
  • Mesothelioma
  • PET/CT
  • Progressive disease
  • Radiotherapy

ASJC Scopus subject areas

  • Oncology
  • Pulmonary and Respiratory Medicine
  • Cancer Research

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