Moderately Hypofractionated Helical IMRT, FDG–PET/CT-guided, for Progressive Malignant Pleural Mesothelioma in Patients With Intact Lungs

Andrei Fodor; Sara Broggi; Elena Incerti; Italo Dell'Oca; Claudio Fiorino; Ana M. Samanes Gajate; Marcella Pasetti; Mauro G. Cattaneo; Paolo Passoni; Luigi Gianolli; Riccardo Calandrino; Maria Picchio; Nadia Di Muzio

doi:10.1016/j.cllc.2018.08.019

Moderately Hypofractionated Helical IMRT, FDG–PET/CT-guided, for Progressive Malignant Pleural Mesothelioma in Patients With Intact Lungs

Andrei Fodor, Sara Broggi, Elena Incerti, Italo Dell'Oca, Claudio Fiorino, Ana M. Samanes Gajate, Marcella Pasetti, Mauro G. Cattaneo, Paolo Passoni, Luigi Gianolli, Riccardo Calandrino, Maria Picchio, Nadia Di Muzio

Research output: Contribution to journal › Article › peer-review

Abstract

Fifty-one patients with malignant pleural mesothelioma treated with helical intensity-modulated radiation therapy in presence of intact lungs were analyzed. A positron emission tomography positive volume ≥ 473 cc was found predictive of early death. A positron emission tomography positive volume < 205 cc was associated with longer survival in stage III to IV patients treated with simultaneous integrated boost, and also with higher late pulmonary ≥ grade 2 toxicity.

Original language	English
Pages (from-to)	e29-e38
Journal	Clinical Lung Cancer
Volume	20
Issue number	1
DOIs	https://doi.org/10.1016/j.cllc.2018.08.019
Publication status	Published - Jan 2019

Keywords

Hypofractionation
Mesothelioma
PET/CT
Progressive disease
Radiotherapy

ASJC Scopus subject areas

Oncology
Pulmonary and Respiratory Medicine
Cancer Research

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10.1016/j.cllc.2018.08.019

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Fodor, A., Broggi, S., Incerti, E., Dell'Oca, I., Fiorino, C., Samanes Gajate, A. M., Pasetti, M., Cattaneo, M. G., Passoni, P., Gianolli, L., Calandrino, R., Picchio, M., & Di Muzio, N. (2019). Moderately Hypofractionated Helical IMRT, FDG–PET/CT-guided, for Progressive Malignant Pleural Mesothelioma in Patients With Intact Lungs. Clinical Lung Cancer, 20(1), e29-e38. https://doi.org/10.1016/j.cllc.2018.08.019

Fodor, A, Broggi, S, Incerti, E, Dell'Oca, I, Fiorino, C, Samanes Gajate, AM, Pasetti, M, Cattaneo, MG, Passoni, P, Gianolli, L, Calandrino, R, Picchio, M & Di Muzio, N 2019, 'Moderately Hypofractionated Helical IMRT, FDG–PET/CT-guided, for Progressive Malignant Pleural Mesothelioma in Patients With Intact Lungs', Clinical Lung Cancer, vol. 20, no. 1, pp. e29-e38. https://doi.org/10.1016/j.cllc.2018.08.019

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title = "Moderately Hypofractionated Helical IMRT, FDG–PET/CT-guided, for Progressive Malignant Pleural Mesothelioma in Patients With Intact Lungs",

abstract = "Fifty-one patients with malignant pleural mesothelioma treated with helical intensity-modulated radiation therapy in presence of intact lungs were analyzed. A positron emission tomography positive volume ≥ 473 cc was found predictive of early death. A positron emission tomography positive volume < 205 cc was associated with longer survival in stage III to IV patients treated with simultaneous integrated boost, and also with higher late pulmonary ≥ grade 2 toxicity.",

keywords = "Hypofractionation, Mesothelioma, PET/CT, Progressive disease, Radiotherapy",

author = "Andrei Fodor and Sara Broggi and Elena Incerti and Italo Dell'Oca and Claudio Fiorino and {Samanes Gajate}, {Ana M.} and Marcella Pasetti and Cattaneo, {Mauro G.} and Paolo Passoni and Luigi Gianolli and Riccardo Calandrino and Maria Picchio and {Di Muzio}, Nadia",

year = "2019",

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doi = "10.1016/j.cllc.2018.08.019",

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AU - Fodor, Andrei

AU - Broggi, Sara

AU - Incerti, Elena

AU - Dell'Oca, Italo

AU - Fiorino, Claudio

AU - Samanes Gajate, Ana M.

AU - Pasetti, Marcella

AU - Cattaneo, Mauro G.

AU - Passoni, Paolo

AU - Gianolli, Luigi

AU - Calandrino, Riccardo

AU - Picchio, Maria

AU - Di Muzio, Nadia

PY - 2019/1

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N2 - Fifty-one patients with malignant pleural mesothelioma treated with helical intensity-modulated radiation therapy in presence of intact lungs were analyzed. A positron emission tomography positive volume ≥ 473 cc was found predictive of early death. A positron emission tomography positive volume < 205 cc was associated with longer survival in stage III to IV patients treated with simultaneous integrated boost, and also with higher late pulmonary ≥ grade 2 toxicity.

AB - Fifty-one patients with malignant pleural mesothelioma treated with helical intensity-modulated radiation therapy in presence of intact lungs were analyzed. A positron emission tomography positive volume ≥ 473 cc was found predictive of early death. A positron emission tomography positive volume < 205 cc was associated with longer survival in stage III to IV patients treated with simultaneous integrated boost, and also with higher late pulmonary ≥ grade 2 toxicity.

KW - Hypofractionation

KW - Mesothelioma

KW - PET/CT

KW - Progressive disease

KW - Radiotherapy

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Moderately Hypofractionated Helical IMRT, FDG–PET/CT-guided, for Progressive Malignant Pleural Mesothelioma in Patients With Intact Lungs

Abstract

Keywords

ASJC Scopus subject areas

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