Modern hemodynamic evaluation of the pulmonary circulation. Application to pulmonary arterial hypertension and embolic pulmonary hypertension

Roberto Naeije, Dario Vizza

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

The hemodynamic evaluation of the pulmonary circulation normally includes the measurements of mean pulmonary artery pressure and a calculation of pulmonary vascular resistance (PVR). The definition of PVR can be improved by the measurements of pulmonary vascular pressures at several levels of flow to derive a pressure-flow line, and the site of PVR can be identified by the analysis of pulmonary artery pressure decay curves after balloon occlusion. An analysis of the morphology of pulmonary artery pressure and flow waves informs about right ventricular (RV) hydraulic load. As pulmonary hypertension is clinically a right heart failure syndrome, it is important to measure the coupling of RV to pulmonary arterial function. This can be done using a single beat method with sampling and synchronization of instantaneous pulmonary artery flow and RV pressure to calculate a ratio of end-systolic to arterial elastances. The optimal value of this ratio is depressed in minimally symptomatic pulmonary arterial hypertension patients, indicating pending right heart failure.

Original languageEnglish
Pages (from-to)784-788
Number of pages5
JournalItalian Heart Journal
Volume6
Issue number10
Publication statusPublished - Oct 2005

Fingerprint

Pulmonary Circulation
Pulmonary Hypertension
Hemodynamics
Pulmonary Artery
Pressure
Vascular Resistance
Heart Failure
Balloon Occlusion
Lung
Ventricular Pressure
Blood Vessels

Keywords

  • Contractility
  • Pulmonary hypertension
  • Pulmonary vascular impedance
  • Pulmonary vascular resistance
  • Right ventricular function

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Modern hemodynamic evaluation of the pulmonary circulation. Application to pulmonary arterial hypertension and embolic pulmonary hypertension. / Naeije, Roberto; Vizza, Dario.

In: Italian Heart Journal, Vol. 6, No. 10, 10.2005, p. 784-788.

Research output: Contribution to journalArticle

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