We analysed cortical excitability in 17 patients with progressive myoclonus epilepsy by means of several neurophysiological ťechniques. The applied tests, including SSEP, long-loop reflex and transcranial magnetic stimulation were able to detect in 16 cases signs of abnormal excitability involving somatosensory or motor cortex. In four cases, topiramate (TPM) induced a significant clinical improvement that corresponded to normalisation of neurophysiological findings.
|Translated title of the contribution||Modification of cortical excitability in progressive myoclonus epilepsy|
|Number of pages||2|
|Journal||Bollettino - Lega Italiana contro l'Epilessia|
|Publication status||Published - 2001|
ASJC Scopus subject areas
- Clinical Neurology