In rats, acutely given alcohol, 5 HIAA brain levels were shown to have increased and HVA brain levels to have fallen, as compared to the controls, possibly because of a different sensitivity of the aldehyde dehydrogenase activities to ethanol inhibition. As a result of inhibition of the oxidative pathway, in rats which chronically drank ethanol, the 5 HIAA brain levels fell; the HVA levels increased more than the controls, perhaps because of a morphine like action of the tetrahydropapaveroline.
|Translated title of the contribution||Modification of levels of homovanillic acid and 5 hydroxyindoleacetic acid in the rat brain after acute and chronic treatment with ethanol|
|Number of pages||7|
|Publication status||Published - 1974|
ASJC Scopus subject areas
- Clinical Neurology