Modified autologous matrix-induced chondrogenesis (AMIC) for the treatment of a large osteochondral defect in a varus knee: A case report

L. de Girolamo; A. Quaglia; C. Bait; M. Cervellin; E. Prospero; P. Volpi

doi:10.1007/s00167-012-2143-y

Modified autologous matrix-induced chondrogenesis (AMIC) for the treatment of a large osteochondral defect in a varus knee: A case report

L. de Girolamo, A. Quaglia, C. Bait, M. Cervellin, E. Prospero, P. Volpi

Research output: Contribution to journal › Article

Abstract

This paper presents a case report of a 27-year-old male patient affected by a large osteochondral defect of the medial femoral condyle (6 cm²) in a varus knee. He was treated with a combined approach consisting of high tibial osteotomy and autologous matrix-induced chondrogenesis technique enhanced by a bone marrow-enriched bone graft. Twelve months after surgery, the patient reported considerable reduction in pain and significant increase in his quality of life. A hyaline-like cartilage completely covered the defect and was congruent with the surrounding condyle cartilage as revealed by MRI and by a second-look arthroscopy. Level of evidence IV.

Original language	English
Pages (from-to)	2287-2290
Number of pages	4
Journal	Knee Surgery, Sports Traumatology, Arthroscopy
Volume	20
Issue number	11
DOIs	https://doi.org/10.1007/s00167-012-2143-y
Publication status	Published - Nov 2012

Keywords

Autologous matrix-induced chondrogenesis
Bone graft
Concentrated bone marrow
Osteochondral lesion
Osteotomy
Varus knee

ASJC Scopus subject areas

Orthopedics and Sports Medicine
Surgery

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de Girolamo, L., Quaglia, A., Bait, C., Cervellin, M., Prospero, E., & Volpi, P. (2012). Modified autologous matrix-induced chondrogenesis (AMIC) for the treatment of a large osteochondral defect in a varus knee: A case report. Knee Surgery, Sports Traumatology, Arthroscopy, 20(11), 2287-2290. https://doi.org/10.1007/s00167-012-2143-y

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AU - Prospero, E.

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