Modified autologous matrix-induced chondrogenesis (AMIC) for the treatment of a large osteochondral defect in a varus knee: A case report

L. de Girolamo, A. Quaglia, C. Bait, M. Cervellin, E. Prospero, P. Volpi

Research output: Contribution to journalArticle

Abstract

This paper presents a case report of a 27-year-old male patient affected by a large osteochondral defect of the medial femoral condyle (6 cm2) in a varus knee. He was treated with a combined approach consisting of high tibial osteotomy and autologous matrix-induced chondrogenesis technique enhanced by a bone marrow-enriched bone graft. Twelve months after surgery, the patient reported considerable reduction in pain and significant increase in his quality of life. A hyaline-like cartilage completely covered the defect and was congruent with the surrounding condyle cartilage as revealed by MRI and by a second-look arthroscopy. Level of evidence IV.

Original languageEnglish
Pages (from-to)2287-2290
Number of pages4
JournalKnee Surgery, Sports Traumatology, Arthroscopy
Volume20
Issue number11
DOIs
Publication statusPublished - Nov 2012

Keywords

  • Autologous matrix-induced chondrogenesis
  • Bone graft
  • Concentrated bone marrow
  • Osteochondral lesion
  • Osteotomy
  • Varus knee

ASJC Scopus subject areas

  • Orthopedics and Sports Medicine
  • Surgery

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