Modulation of gamma and theta spectral amplitude and phase synchronization is associated with the development of visuo-motor learning

Bernardo Perfetti, Clara Moisello, Eric Carl Landsness, Svetlana Kvint, Simona Lanzafame, Marco Onofrj, Alessandro di Rocco, Giulio Tononi, M. Felice Ghilardi

Research output: Contribution to journalArticle

47 Citations (Scopus)

Abstract

The formation of new motor memories, which is fundamental for efficient performance during adaptation to a visuo-motor rotation, occurs when accurate planning is achieved mostly with feedforward mechanisms. The dynamics of brain activity underlying the switch from feedback to feedforward control is still matter of debate. Based on the results of studies in declarative learning, it is likely that phase synchronization of low and high frequencies as well as their temporal modulation in power amplitude underlie the formation of new motor memories during visuo-motor adaptation. High-density EEG (256 electrodes) was recorded in 17 normal human subjects during adaptation to a visuo-motor rotation of 60° in four incremental steps of 15°.Wefound that initial learning is associated with enhancement of gamma power in a right parietal region during movement execution as well as gamma/theta phase coherence during movement planning. Late stages of learning are instead accompanied by an increase of theta power over that same right parietal region during movement planning, which is correlated with the degree of learning and retention. Altogether, these results suggest that the formation of new motor memories and, thus, the switch from feedback to feedforward control is associated with the modulation of gamma and theta spectral activities, with respect to their amplitude and phase, during movement planning and execution. Specifically, we propose that gamma/theta phase coupling plays a pivotal role in the integration of a new representation into motor memories.

Original languageEnglish
Pages (from-to)14810-14819
Number of pages10
JournalJournal of Neuroscience
Volume31
Issue number41
DOIs
Publication statusPublished - Oct 12 2011

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Learning
Parietal Lobe
Electroencephalography
Electrodes
Brain
Power (Psychology)
Retention (Psychology)

ASJC Scopus subject areas

  • Neuroscience(all)

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Perfetti, B., Moisello, C., Landsness, E. C., Kvint, S., Lanzafame, S., Onofrj, M., ... Felice Ghilardi, M. (2011). Modulation of gamma and theta spectral amplitude and phase synchronization is associated with the development of visuo-motor learning. Journal of Neuroscience, 31(41), 14810-14819. https://doi.org/10.1523/JNEUROSCI.1319-11.2011

Modulation of gamma and theta spectral amplitude and phase synchronization is associated with the development of visuo-motor learning. / Perfetti, Bernardo; Moisello, Clara; Landsness, Eric Carl; Kvint, Svetlana; Lanzafame, Simona; Onofrj, Marco; di Rocco, Alessandro; Tononi, Giulio; Felice Ghilardi, M.

In: Journal of Neuroscience, Vol. 31, No. 41, 12.10.2011, p. 14810-14819.

Research output: Contribution to journalArticle

Perfetti, B, Moisello, C, Landsness, EC, Kvint, S, Lanzafame, S, Onofrj, M, di Rocco, A, Tononi, G & Felice Ghilardi, M 2011, 'Modulation of gamma and theta spectral amplitude and phase synchronization is associated with the development of visuo-motor learning', Journal of Neuroscience, vol. 31, no. 41, pp. 14810-14819. https://doi.org/10.1523/JNEUROSCI.1319-11.2011
Perfetti, Bernardo ; Moisello, Clara ; Landsness, Eric Carl ; Kvint, Svetlana ; Lanzafame, Simona ; Onofrj, Marco ; di Rocco, Alessandro ; Tononi, Giulio ; Felice Ghilardi, M. / Modulation of gamma and theta spectral amplitude and phase synchronization is associated with the development of visuo-motor learning. In: Journal of Neuroscience. 2011 ; Vol. 31, No. 41. pp. 14810-14819.
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