Modulation of production of hepatitis B surface antigen by a human hepatoma cell line

M. Clementi, P. Bagnarelli, P. Pauri, L. Calegari

Research output: Contribution to journalArticle

Abstract

Three drugs were assayed for their capacity to inhibit hepatitis B surface antigen (HBsAg) production by the PLC/PRF/5 human hepatoma cell line. The effect on cell growth and HBsAg production of Cordycepin, 6-azauridine, and Hygromicin B is reported. Hygromicin B, a translation inhibitor unable to penetrate normal cells, greatly reduced HBsAg production by growing and confluent cells.

Original languageEnglish
Pages (from-to)117-123
Number of pages7
JournalJournal of Medical Virology
Volume13
Issue number2
Publication statusPublished - 1984

ASJC Scopus subject areas

  • Virology

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