Modulation of T cell-mediated immune responses by natural killer cells

Alessandra Zingoni, Cristina Cerboni, Michele Ardolino, Angela Santoni

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Natural Killer (NK) cells are lymphoid cells that participate in innate immunity and in early defense against infections and tumors. NK cells express cell surface activating and inhibitory receptors that allow them to recognize and kill infected or tumor cells and rapidly produce cytokines and chemokines. Increasing evidence asserts an important immunomodulatory role of NK cells. We will discuss different mechanisms used by NK cells to regulate T cell-mediated immune responses.

Original languageEnglish
Title of host publicationNatural Killer Cells: At the Forefront of Modern Immunology
PublisherSpringer Berlin Heidelberg
Pages315-327
Number of pages13
ISBN (Print)9783642023088
DOIs
Publication statusPublished - 2010

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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