Abstract
Polygraphic sleep recordings (EEG, EMG, and EOG) were performed in two groups of epileptic subjects, six with fragile-X syndrome and six with symptomatic epilepsy. Recordings were visually scored for sleep stages and number of spikes/min. Subjects with fragile-X syndrome showed a well defined pattern of production of interictal epileptiform activity with the lowest values during REM sleep; symptomatic epileptic subjects showed less defined and more variable spike/min diagrams. The spectral analysis of the outline of such diagrams confirmed these differences showing shorter periodicties (80-100 min) in the fragile-X group compared to those of the symptomatic group (160-220 min). Finally, a model with multiple feedback circuits is proposed in order to explain the different patterns observed.
| Original language | English |
|---|---|
| Pages (from-to) | 1-14 |
| Number of pages | 14 |
| Journal | Neurophysiologie Clinique / Clinical Neurophysiology |
| Volume | 21 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - 1991 |
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Keywords
- epilepsy
- sleep
ASJC Scopus subject areas
- Clinical Neurology
- Neuroscience(all)
Cite this
Modulation of the interictal epileptiform EEG activity during sleep : from oscillations to complex dynamics. / Ferri, R.; Bergonzi, P.; Elia, M.; Ferri, P.; Musumeci, S. A.
In: Neurophysiologie Clinique / Clinical Neurophysiology, Vol. 21, No. 1, 1991, p. 1-14.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Modulation of the interictal epileptiform EEG activity during sleep
T2 - from oscillations to complex dynamics
AU - Ferri, R.
AU - Bergonzi, P.
AU - Elia, M.
AU - Ferri, P.
AU - Musumeci, S. A.
PY - 1991
Y1 - 1991
N2 - Polygraphic sleep recordings (EEG, EMG, and EOG) were performed in two groups of epileptic subjects, six with fragile-X syndrome and six with symptomatic epilepsy. Recordings were visually scored for sleep stages and number of spikes/min. Subjects with fragile-X syndrome showed a well defined pattern of production of interictal epileptiform activity with the lowest values during REM sleep; symptomatic epileptic subjects showed less defined and more variable spike/min diagrams. The spectral analysis of the outline of such diagrams confirmed these differences showing shorter periodicties (80-100 min) in the fragile-X group compared to those of the symptomatic group (160-220 min). Finally, a model with multiple feedback circuits is proposed in order to explain the different patterns observed.
AB - Polygraphic sleep recordings (EEG, EMG, and EOG) were performed in two groups of epileptic subjects, six with fragile-X syndrome and six with symptomatic epilepsy. Recordings were visually scored for sleep stages and number of spikes/min. Subjects with fragile-X syndrome showed a well defined pattern of production of interictal epileptiform activity with the lowest values during REM sleep; symptomatic epileptic subjects showed less defined and more variable spike/min diagrams. The spectral analysis of the outline of such diagrams confirmed these differences showing shorter periodicties (80-100 min) in the fragile-X group compared to those of the symptomatic group (160-220 min). Finally, a model with multiple feedback circuits is proposed in order to explain the different patterns observed.
KW - epilepsy
KW - sleep
UR - http://www.scopus.com/inward/record.url?scp=0026024327&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0026024327&partnerID=8YFLogxK
U2 - 10.1016/S0987-7053(05)80349-1
DO - 10.1016/S0987-7053(05)80349-1
M3 - Article
C2 - 2062267
AN - SCOPUS:0026024327
VL - 21
SP - 1
EP - 14
JO - Neurophysiologie Clinique
JF - Neurophysiologie Clinique
SN - 0987-7053
IS - 1
ER -