Modulation of the interictal epileptiform EEG activity during sleep: from oscillations to complex dynamics

R. Ferri, P. Bergonzi, M. Elia, P. Ferri, S. A. Musumeci

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Polygraphic sleep recordings (EEG, EMG, and EOG) were performed in two groups of epileptic subjects, six with fragile-X syndrome and six with symptomatic epilepsy. Recordings were visually scored for sleep stages and number of spikes/min. Subjects with fragile-X syndrome showed a well defined pattern of production of interictal epileptiform activity with the lowest values during REM sleep; symptomatic epileptic subjects showed less defined and more variable spike/min diagrams. The spectral analysis of the outline of such diagrams confirmed these differences showing shorter periodicties (80-100 min) in the fragile-X group compared to those of the symptomatic group (160-220 min). Finally, a model with multiple feedback circuits is proposed in order to explain the different patterns observed.

Original languageEnglish
Pages (from-to)1-14
Number of pages14
JournalNeurophysiologie Clinique / Clinical Neurophysiology
Volume21
Issue number1
DOIs
Publication statusPublished - 1991

Fingerprint

Electrooculography
Fragile X Syndrome
Sleep
Sleep Stages
REM Sleep
Epilepsy

Keywords

  • epilepsy
  • sleep

ASJC Scopus subject areas

  • Clinical Neurology
  • Neuroscience(all)

Cite this

@article{cf76e735f2474259ab284fe60d374b18,
title = "Modulation of the interictal epileptiform EEG activity during sleep: from oscillations to complex dynamics",
abstract = "Polygraphic sleep recordings (EEG, EMG, and EOG) were performed in two groups of epileptic subjects, six with fragile-X syndrome and six with symptomatic epilepsy. Recordings were visually scored for sleep stages and number of spikes/min. Subjects with fragile-X syndrome showed a well defined pattern of production of interictal epileptiform activity with the lowest values during REM sleep; symptomatic epileptic subjects showed less defined and more variable spike/min diagrams. The spectral analysis of the outline of such diagrams confirmed these differences showing shorter periodicties (80-100 min) in the fragile-X group compared to those of the symptomatic group (160-220 min). Finally, a model with multiple feedback circuits is proposed in order to explain the different patterns observed.",
keywords = "epilepsy, sleep",
author = "R. Ferri and P. Bergonzi and M. Elia and P. Ferri and Musumeci, {S. A.}",
year = "1991",
doi = "10.1016/S0987-7053(05)80349-1",
language = "English",
volume = "21",
pages = "1--14",
journal = "Neurophysiologie Clinique",
issn = "0987-7053",
publisher = "Elsevier Masson",
number = "1",

}

TY - JOUR

T1 - Modulation of the interictal epileptiform EEG activity during sleep

T2 - from oscillations to complex dynamics

AU - Ferri, R.

AU - Bergonzi, P.

AU - Elia, M.

AU - Ferri, P.

AU - Musumeci, S. A.

PY - 1991

Y1 - 1991

N2 - Polygraphic sleep recordings (EEG, EMG, and EOG) were performed in two groups of epileptic subjects, six with fragile-X syndrome and six with symptomatic epilepsy. Recordings were visually scored for sleep stages and number of spikes/min. Subjects with fragile-X syndrome showed a well defined pattern of production of interictal epileptiform activity with the lowest values during REM sleep; symptomatic epileptic subjects showed less defined and more variable spike/min diagrams. The spectral analysis of the outline of such diagrams confirmed these differences showing shorter periodicties (80-100 min) in the fragile-X group compared to those of the symptomatic group (160-220 min). Finally, a model with multiple feedback circuits is proposed in order to explain the different patterns observed.

AB - Polygraphic sleep recordings (EEG, EMG, and EOG) were performed in two groups of epileptic subjects, six with fragile-X syndrome and six with symptomatic epilepsy. Recordings were visually scored for sleep stages and number of spikes/min. Subjects with fragile-X syndrome showed a well defined pattern of production of interictal epileptiform activity with the lowest values during REM sleep; symptomatic epileptic subjects showed less defined and more variable spike/min diagrams. The spectral analysis of the outline of such diagrams confirmed these differences showing shorter periodicties (80-100 min) in the fragile-X group compared to those of the symptomatic group (160-220 min). Finally, a model with multiple feedback circuits is proposed in order to explain the different patterns observed.

KW - epilepsy

KW - sleep

UR - http://www.scopus.com/inward/record.url?scp=0026024327&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0026024327&partnerID=8YFLogxK

U2 - 10.1016/S0987-7053(05)80349-1

DO - 10.1016/S0987-7053(05)80349-1

M3 - Article

C2 - 2062267

AN - SCOPUS:0026024327

VL - 21

SP - 1

EP - 14

JO - Neurophysiologie Clinique

JF - Neurophysiologie Clinique

SN - 0987-7053

IS - 1

ER -