Molecular analysis of clinical isolates of Mycobacterium bovis recovered from humans in Italy

Nicoletta Lari, Laura Rindi, Daniela Bonanni, Enrico Tortoli, Carlo Garzelli

Research output: Contribution to journalArticle

Abstract

In order to achieve a better knowledge of Mycobacterium bovis epidemiology in Italy, 42 clinical isolates from humans were genotyped. Predominant molecular patterns were found in one cluster of 15 isolates sharing spoligotype (ST482), variable-number tandem repeat (VNTR), and IS6110-based restriction fragment length polymorphism (one 1.9-kb band) profiles and in two clusters of 6 and 3 Mycobacterium bovis BCG isolates differing by one VNTR character. The remaining 18 isolates yielded unique profiles. Our results confirm the potential utility of spoligotyping and VNTR typing as a major typing system of M. bovis isolates.

Original languageEnglish
Pages (from-to)4218-4221
Number of pages4
JournalJournal of Clinical Microbiology
Volume44
Issue number11
DOIs
Publication statusPublished - Nov 2006

ASJC Scopus subject areas

  • Microbiology (medical)
  • Microbiology

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