Molecular analysis of clinical isolates of Mycobacterium bovis recovered from humans in Italy

Nicoletta Lari, Laura Rindi, Daniela Bonanni, Enrico Tortoli, Carlo Garzelli

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

In order to achieve a better knowledge of Mycobacterium bovis epidemiology in Italy, 42 clinical isolates from humans were genotyped. Predominant molecular patterns were found in one cluster of 15 isolates sharing spoligotype (ST482), variable-number tandem repeat (VNTR), and IS6110-based restriction fragment length polymorphism (one 1.9-kb band) profiles and in two clusters of 6 and 3 Mycobacterium bovis BCG isolates differing by one VNTR character. The remaining 18 isolates yielded unique profiles. Our results confirm the potential utility of spoligotyping and VNTR typing as a major typing system of M. bovis isolates.

Original languageEnglish
Pages (from-to)4218-4221
Number of pages4
JournalJournal of Clinical Microbiology
Volume44
Issue number11
DOIs
Publication statusPublished - Nov 2006

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Mycobacterium bovis
Minisatellite Repeats
Italy
Restriction Fragment Length Polymorphisms
Epidemiology

ASJC Scopus subject areas

  • Microbiology (medical)
  • Microbiology

Cite this

Molecular analysis of clinical isolates of Mycobacterium bovis recovered from humans in Italy. / Lari, Nicoletta; Rindi, Laura; Bonanni, Daniela; Tortoli, Enrico; Garzelli, Carlo.

In: Journal of Clinical Microbiology, Vol. 44, No. 11, 11.2006, p. 4218-4221.

Research output: Contribution to journalArticle

Lari, Nicoletta ; Rindi, Laura ; Bonanni, Daniela ; Tortoli, Enrico ; Garzelli, Carlo. / Molecular analysis of clinical isolates of Mycobacterium bovis recovered from humans in Italy. In: Journal of Clinical Microbiology. 2006 ; Vol. 44, No. 11. pp. 4218-4221.
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