Abstract
An 18-month-old Arabian foal characterized by a stallionlike appearance was submitted for cytogenetic and molecular genetics examinations due to abnormalities of external genitalia and the presence of ovotestis-like structures in the abdominal cavity. By RB-banding the animal showed the normal female equine karyotype (2n = 64,XX). Molecular analysis revealed the absence of the SRY and ZFY genes and the presence of ZFX , a typical female equine condition. The entire RSPO1 coding region was examined to exclude its involvement. Although a SNP was found in exon 3, it was not responsible for an amino acid substitution.
Original language | English |
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Pages (from-to) | 104-107 |
Number of pages | 4 |
Journal | Sexual Development |
Volume | 6 |
Issue number | 1-3 |
DOIs | |
Publication status | Published - Feb 2012 |
Keywords
- Arabian horse
- RSPO1
- Sex reversal syndrome
- SRY
- ZFX/ZFY
ASJC Scopus subject areas
- Developmental Biology
- Embryology
- Endocrinology, Diabetes and Metabolism
- Medicine(all)