Molecular biology and genetics

Francesco Cetta

Research output: Chapter in Book/Report/Conference proceedingChapter


Hepatocellular benign tumors are characterized by benign proliferation of hepatocytes with a mass-forming presentation and mainly consist of hepatocellular adenoma (HA) and focal nodular hyperplasia (FNH) [1, 2]. HA and FNH share common features. First, a large female preponderance has been found in both diseases, with a female/male ratio=8: 1 for FNH and 9: 1 for HA. In addition, FNH and HA derive from the proliferation of mature hepatocytes and arise on an otherwise normal liver. Therefore, they represent a model to study liver tumorigenesis outside the classic background of cirrhosis [2].

Original languageEnglish
Title of host publicationBenign Tumors of the Liver
PublisherSpringer International Publishing
Number of pages12
ISBN (Print)9783319129853, 9783319129846
Publication statusPublished - Jan 1 2015

ASJC Scopus subject areas

  • Medicine(all)
  • Biochemistry, Genetics and Molecular Biology(all)


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