La biologia molecolare nella diagnosi e nella valutazione della malattia residua minima nella leucemia linfoblastica acuta del bambino

M. Lanciotti; C. Micalizzi; F. Scuderi; D. Di Martino; G. Dini

La biologia molecolare nella diagnosi e nella valutazione della malattia residua minima nella leucemia linfoblastica acuta del bambino

Translated title of the contribution: Molecular biology in the diagnosis and evaluation of minimal residual disease in pediatric acute lymphoblastic leukemia

M. Lanciotti, C. Micalizzi, F. Scuderi, D. Di Martino, G. Dini

Istituto "Giannina Gaslini"

Research output: Contribution to journal › Article › peer-review

Abstract

The molecular approach to the study of minimal residual disease (MRD) in pediatric acute lymphoblastic leukemia (ALL) underlines the importance of the molecular techniques in the hematology and oncology fields. The possibility to reach a 'molecular remission' after the induction therapy is the most important goal to cure the leukemia. We report the most frequently used markers for MRD detection in pediatric ALL and the results obtained.

Translated title of the contribution	Molecular biology in the diagnosis and evaluation of minimal residual disease in pediatric acute lymphoblastic leukemia
Original language	Italian
Pages (from-to)	56-69
Number of pages	14
Journal	Gaslini
Volume	33
Issue number	1
Publication status	Published - 2001

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health

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Cite this

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abstract = "The molecular approach to the study of minimal residual disease (MRD) in pediatric acute lymphoblastic leukemia (ALL) underlines the importance of the molecular techniques in the hematology and oncology fields. The possibility to reach a 'molecular remission' after the induction therapy is the most important goal to cure the leukemia. We report the most frequently used markers for MRD detection in pediatric ALL and the results obtained.",

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AU - Micalizzi, C.

AU - Scuderi, F.

AU - Di Martino, D.

AU - Dini, G.

PY - 2001

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N2 - The molecular approach to the study of minimal residual disease (MRD) in pediatric acute lymphoblastic leukemia (ALL) underlines the importance of the molecular techniques in the hematology and oncology fields. The possibility to reach a 'molecular remission' after the induction therapy is the most important goal to cure the leukemia. We report the most frequently used markers for MRD detection in pediatric ALL and the results obtained.

AB - The molecular approach to the study of minimal residual disease (MRD) in pediatric acute lymphoblastic leukemia (ALL) underlines the importance of the molecular techniques in the hematology and oncology fields. The possibility to reach a 'molecular remission' after the induction therapy is the most important goal to cure the leukemia. We report the most frequently used markers for MRD detection in pediatric ALL and the results obtained.

KW - Acute lymphoblastic leukemia

KW - Minimal residual disease

KW - Translocations

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