Molecular characterization of glucose-6-phosphate dehydrogenase deficiency in the Fars province of Iran

Mehran Karimi, Franco Martinez Di Mantemuras, María Gabriella Danielli, Shirin Farjadian, Abdolreza Afrasiabi, Gemino Fiorelli, Maria Domenica Cappellini

Research output: Contribution to journalArticle

22 Citations (Scopus)

Abstract

We investigated 78 glucose-6-phosphate dehydrogenase (G6PD)-deficient alleles from the Fars province of Iran by polymerase chain reaction-single strand conformation polymorphism (PCR-SSCP) and direct sequencing. The frequency of G6PD Mediterranean in Fars was 84.6%, G6PD Chatham was found to be highly polymorphic and two other sporadic variants (G6PD A- and G6PD Canton) were detected in single cases.

Original languageEnglish
Pages (from-to)346-347
Number of pages2
JournalHaematologica
Volume88
Issue number3
Publication statusPublished - Mar 1 2003

Fingerprint

Glucosephosphate Dehydrogenase Deficiency
Glucosephosphate Dehydrogenase
Iran
Alleles
Polymerase Chain Reaction

Keywords

  • G6PD deficiency
  • G6PD mutations
  • Iran
  • Molecular characterization

ASJC Scopus subject areas

  • Hematology

Cite this

Karimi, M., Di Mantemuras, F. M., Danielli, M. G., Farjadian, S., Afrasiabi, A., Fiorelli, G., & Cappellini, M. D. (2003). Molecular characterization of glucose-6-phosphate dehydrogenase deficiency in the Fars province of Iran. Haematologica, 88(3), 346-347.

Molecular characterization of glucose-6-phosphate dehydrogenase deficiency in the Fars province of Iran. / Karimi, Mehran; Di Mantemuras, Franco Martinez; Danielli, María Gabriella; Farjadian, Shirin; Afrasiabi, Abdolreza; Fiorelli, Gemino; Cappellini, Maria Domenica.

In: Haematologica, Vol. 88, No. 3, 01.03.2003, p. 346-347.

Research output: Contribution to journalArticle

Karimi, M, Di Mantemuras, FM, Danielli, MG, Farjadian, S, Afrasiabi, A, Fiorelli, G & Cappellini, MD 2003, 'Molecular characterization of glucose-6-phosphate dehydrogenase deficiency in the Fars province of Iran', Haematologica, vol. 88, no. 3, pp. 346-347.
Karimi M, Di Mantemuras FM, Danielli MG, Farjadian S, Afrasiabi A, Fiorelli G et al. Molecular characterization of glucose-6-phosphate dehydrogenase deficiency in the Fars province of Iran. Haematologica. 2003 Mar 1;88(3):346-347.
Karimi, Mehran ; Di Mantemuras, Franco Martinez ; Danielli, María Gabriella ; Farjadian, Shirin ; Afrasiabi, Abdolreza ; Fiorelli, Gemino ; Cappellini, Maria Domenica. / Molecular characterization of glucose-6-phosphate dehydrogenase deficiency in the Fars province of Iran. In: Haematologica. 2003 ; Vol. 88, No. 3. pp. 346-347.
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