Molecular characterization of glucose-6-phosphate dehydrogenase deficiency in the Fars province of Iran

Mehran Karimi, Franco Martinez Di Mantemuras, María Gabriella Danielli, Shirin Farjadian, Abdolreza Afrasiabi, Gemino Fiorelli, Maria Domenica Cappellini

Research output: Contribution to journalArticlepeer-review

Abstract

We investigated 78 glucose-6-phosphate dehydrogenase (G6PD)-deficient alleles from the Fars province of Iran by polymerase chain reaction-single strand conformation polymorphism (PCR-SSCP) and direct sequencing. The frequency of G6PD Mediterranean in Fars was 84.6%, G6PD Chatham was found to be highly polymorphic and two other sporadic variants (G6PD A- and G6PD Canton) were detected in single cases.

Original languageEnglish
Pages (from-to)346-347
Number of pages2
JournalHaematologica
Volume88
Issue number3
Publication statusPublished - Mar 1 2003

Keywords

  • G6PD deficiency
  • G6PD mutations
  • Iran
  • Molecular characterization

ASJC Scopus subject areas

  • Hematology

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