Molecular characterization of hepatitis A outbreak in the province of Rome, Lazio region, Italy, January-July 2013

Maria R. Capobianchi; Anna Rosa Garbuglia; Chiara Agrati; Alessia Rianda; Pasquale Noto; Angela Corpolongo; Maria Adriana Cataldo; Silvia Rosati; Paola Zaccaro; Mariarosaria Loffredo; Maria Grazia Pompa; Enrico Girardi; Paola Scognamiglio; Giuseppe Ippolito; Andrea Antinori; Gianpiero D'Offizi; Nicola Petrosillo; Fabrizio Palmieri; Giuseppina Nurra; Annamaria Casalanguida; Annamaria Ciufoli; Antonella Petrecchia; Amina Abdeddaim; Franco Baldini; Alessandro Capone; Pierangelo Chinello; Stefania Cicalini; Luigi Cirino; Angela Corpolongo; Vincenzo Galati; Piero Ghirga; Letizia Giancola; Fabio Iacomi; Rita Maddaluno; Andrea Mariano; Paola Mencarini; Alessandra Oliva; Fabrizio Taglietti; Simone Topino; Laura Vincenzi

doi:10.1016/j.micinf.2014.01.003

Molecular characterization of hepatitis A outbreak in the province of Rome, Lazio region, Italy, January-July 2013

Maria R. Capobianchi, Anna Rosa Garbuglia, Chiara Agrati, Alessia Rianda, Pasquale Noto, Angela Corpolongo, Maria Adriana Cataldo, Silvia Rosati, Paola Zaccaro, Mariarosaria Loffredo, Maria Grazia Pompa, Enrico Girardi, Paola Scognamiglio, Giuseppe Ippolito, Andrea Antinori, Gianpiero D'Offizi, Nicola Petrosillo, Fabrizio Palmieri, Giuseppina Nurra, Annamaria CasalanguidaAnnamaria Ciufoli, Antonella Petrecchia, Amina Abdeddaim, Franco Baldini, Alessandro Capone, Pierangelo Chinello, Stefania Cicalini, Luigi Cirino, Angela Corpolongo, Vincenzo Galati, Piero Ghirga, Letizia Giancola, Fabio Iacomi, Rita Maddaluno, Andrea Mariano, Paola Mencarini, Alessandra Oliva, Fabrizio Taglietti, Simone Topino, Laura Vincenzi

Istituto Nazionale per le Malattie Infettive Lazzaro Spallanzani

Research output: Contribution to journal › Article

Abstract

Reduced circulation of hepatitis A virus lead to an increase of susceptible individuals, and outbreaks occurred recently. In Northern Italy an outbreak is ongoing, attributed to a monophyletic genotype IA strain, with mixed frozen berries as probable source. From 01/01/2013 to 07/15/2013, 30 cases were diagnosed at National Institute for Infectious Diseases, Rome, Italy, representing about twice the number of cases in whole 2012. Phylogenetic analysis indicated that most, although not all, infections were attributable to the same monophyletic genotype IA strain identified in the contemporary Northern Italy outbreak. This strain is also very similar to previous isolates from Venezuela.

Original language	English
Pages (from-to)	362-366
Number of pages	5
Journal	Microbes and Infection
Volume	16
Issue number	4
DOIs	https://doi.org/10.1016/j.micinf.2014.01.003
Publication status	Published - 2014

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Keywords

Food-borne infections
Hepatitis A
Molecular characterization
Outbreak
Vaccine-preventable diseases

ASJC Scopus subject areas

Microbiology
Immunology
Infectious Diseases
Medicine(all)

Cite this

Capobianchi, M. R., Garbuglia, A. R., Agrati, C., Rianda, A., Noto, P., Corpolongo, A., Cataldo, M. A., Rosati, S., Zaccaro, P., Loffredo, M., Pompa, M. G., Girardi, E., Scognamiglio, P., Ippolito, G., Antinori, A., D'Offizi, G., Petrosillo, N., Palmieri, F., Nurra, G., ... Vincenzi, L. (2014). Molecular characterization of hepatitis A outbreak in the province of Rome, Lazio region, Italy, January-July 2013. Microbes and Infection, 16(4), 362-366. https://doi.org/10.1016/j.micinf.2014.01.003

Molecular characterization of hepatitis A outbreak in the province of Rome, Lazio region, Italy, January-July 2013. / Capobianchi, Maria R.; Garbuglia, Anna Rosa ; Agrati, Chiara ; Rianda, Alessia ; Noto, Pasquale; Corpolongo, Angela; Cataldo, Maria Adriana ; Rosati, Silvia; Zaccaro, Paola; Loffredo, Mariarosaria; Pompa, Maria Grazia; Girardi, Enrico ; Scognamiglio, Paola ; Ippolito, Giuseppe ; Antinori, Andrea ; D'Offizi, Gianpiero ; Petrosillo, Nicola ; Palmieri, Fabrizio; Nurra, Giuseppina; Casalanguida, Annamaria; Ciufoli, Annamaria; Petrecchia, Antonella ; Abdeddaim, Amina ; Baldini, Franco ; Capone, Alessandro ; Chinello, Pierangelo ; Cicalini, Stefania; Cirino, Luigi; Corpolongo, Angela ; Galati, Vincenzo ; Ghirga, Piero ; Giancola, Letizia ; Iacomi, Fabio ; Maddaluno, Rita ; Mariano, Andrea ; Mencarini, Paola ; Oliva, Alessandra ; Taglietti, Fabrizio ; Topino, Simone ; Vincenzi, Laura.

In: Microbes and Infection, Vol. 16, No. 4, 2014, p. 362-366.

Research output: Contribution to journal › Article

Capobianchi, MR , Garbuglia, AR , Agrati, C , Rianda, A , Noto, P, Corpolongo, A, Cataldo, MA , Rosati, S, Zaccaro, P, Loffredo, M, Pompa, MG, Girardi, E , Scognamiglio, P , Ippolito, G , Antinori, A , D'Offizi, G , Petrosillo, N , Palmieri, F, Nurra, G, Casalanguida, A, Ciufoli, A, Petrecchia, A , Abdeddaim, A , Baldini, F , Capone, A , Chinello, P , Cicalini, S, Cirino, L, Corpolongo, A , Galati, V , Ghirga, P , Giancola, L , Iacomi, F , Maddaluno, R , Mariano, A , Mencarini, P , Oliva, A , Taglietti, F , Topino, S & Vincenzi, L 2014, 'Molecular characterization of hepatitis A outbreak in the province of Rome, Lazio region, Italy, January-July 2013', Microbes and Infection, vol. 16, no. 4, pp. 362-366. https://doi.org/10.1016/j.micinf.2014.01.003

Capobianchi, Maria R. ; Garbuglia, Anna Rosa ; Agrati, Chiara ; Rianda, Alessia ; Noto, Pasquale ; Corpolongo, Angela ; Cataldo, Maria Adriana ; Rosati, Silvia ; Zaccaro, Paola ; Loffredo, Mariarosaria ; Pompa, Maria Grazia ; Girardi, Enrico ; Scognamiglio, Paola ; Ippolito, Giuseppe ; Antinori, Andrea ; D'Offizi, Gianpiero ; Petrosillo, Nicola ; Palmieri, Fabrizio ; Nurra, Giuseppina ; Casalanguida, Annamaria ; Ciufoli, Annamaria ; Petrecchia, Antonella ; Abdeddaim, Amina ; Baldini, Franco ; Capone, Alessandro ; Chinello, Pierangelo ; Cicalini, Stefania ; Cirino, Luigi ; Corpolongo, Angela ; Galati, Vincenzo ; Ghirga, Piero ; Giancola, Letizia ; Iacomi, Fabio ; Maddaluno, Rita ; Mariano, Andrea ; Mencarini, Paola ; Oliva, Alessandra ; Taglietti, Fabrizio ; Topino, Simone ; Vincenzi, Laura. / Molecular characterization of hepatitis A outbreak in the province of Rome, Lazio region, Italy, January-July 2013. In: Microbes and Infection. 2014 ; Vol. 16, No. 4. pp. 362-366.

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abstract = "Reduced circulation of hepatitis A virus lead to an increase of susceptible individuals, and outbreaks occurred recently. In Northern Italy an outbreak is ongoing, attributed to a monophyletic genotype IA strain, with mixed frozen berries as probable source. From 01/01/2013 to 07/15/2013, 30 cases were diagnosed at National Institute for Infectious Diseases, Rome, Italy, representing about twice the number of cases in whole 2012. Phylogenetic analysis indicated that most, although not all, infections were attributable to the same monophyletic genotype IA strain identified in the contemporary Northern Italy outbreak. This strain is also very similar to previous isolates from Venezuela.",

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10.1016/j.micinf.2014.01.003