Molecular characterization of hepatitis A outbreak in the province of Rome, Lazio region, Italy, January-July 2013

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3 Citations (Scopus)

Abstract

Reduced circulation of hepatitis A virus lead to an increase of susceptible individuals, and outbreaks occurred recently. In Northern Italy an outbreak is ongoing, attributed to a monophyletic genotype IA strain, with mixed frozen berries as probable source. From 01/01/2013 to 07/15/2013, 30 cases were diagnosed at National Institute for Infectious Diseases, Rome, Italy, representing about twice the number of cases in whole 2012. Phylogenetic analysis indicated that most, although not all, infections were attributable to the same monophyletic genotype IA strain identified in the contemporary Northern Italy outbreak. This strain is also very similar to previous isolates from Venezuela.

Original languageEnglish
Pages (from-to)362-366
Number of pages5
JournalMicrobes and Infection
Volume16
Issue number4
DOIs
Publication statusPublished - 2014

Fingerprint

Hepatitis A
Italy
Disease Outbreaks
Genotype
Hepatitis A virus
Venezuela
Communicable Diseases
Fruit
Infection

Keywords

  • Food-borne infections
  • Hepatitis A
  • Molecular characterization
  • Outbreak
  • Vaccine-preventable diseases

ASJC Scopus subject areas

  • Microbiology
  • Immunology
  • Infectious Diseases
  • Medicine(all)

Cite this

@article{a346f7c9c9614e51a1db7560618839cc,
title = "Molecular characterization of hepatitis A outbreak in the province of Rome, Lazio region, Italy, January-July 2013",
abstract = "Reduced circulation of hepatitis A virus lead to an increase of susceptible individuals, and outbreaks occurred recently. In Northern Italy an outbreak is ongoing, attributed to a monophyletic genotype IA strain, with mixed frozen berries as probable source. From 01/01/2013 to 07/15/2013, 30 cases were diagnosed at National Institute for Infectious Diseases, Rome, Italy, representing about twice the number of cases in whole 2012. Phylogenetic analysis indicated that most, although not all, infections were attributable to the same monophyletic genotype IA strain identified in the contemporary Northern Italy outbreak. This strain is also very similar to previous isolates from Venezuela.",
keywords = "Food-borne infections, Hepatitis A, Molecular characterization, Outbreak, Vaccine-preventable diseases",
author = "Capobianchi, {Maria R.} and Garbuglia, {Anna Rosa} and Chiara Agrati and Alessia Rianda and Pasquale Noto and Angela Corpolongo and Cataldo, {Maria Adriana} and Silvia Rosati and Paola Zaccaro and Mariarosaria Loffredo and Pompa, {Maria Grazia} and Enrico Girardi and Paola Scognamiglio and Giuseppe Ippolito and Andrea Antinori and Gianpiero D'Offizi and Nicola Petrosillo and Fabrizio Palmieri and Giuseppina Nurra and Annamaria Casalanguida and Annamaria Ciufoli and Antonella Petrecchia and Amina Abdeddaim and Franco Baldini and Alessandro Capone and Pierangelo Chinello and Stefania Cicalini and Luigi Cirino and Angela Corpolongo and Vincenzo Galati and Piero Ghirga and Letizia Giancola and Fabio Iacomi and Rita Maddaluno and Andrea Mariano and Paola Mencarini and Alessandra Oliva and Fabrizio Taglietti and Simone Topino and Laura Vincenzi",
year = "2014",
doi = "10.1016/j.micinf.2014.01.003",
language = "English",
volume = "16",
pages = "362--366",
journal = "Microbes and Infection",
issn = "1286-4579",
publisher = "Elsevier Masson SAS",
number = "4",

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TY - JOUR

T1 - Molecular characterization of hepatitis A outbreak in the province of Rome, Lazio region, Italy, January-July 2013

AU - Capobianchi, Maria R.

AU - Garbuglia, Anna Rosa

AU - Agrati, Chiara

AU - Rianda, Alessia

AU - Noto, Pasquale

AU - Corpolongo, Angela

AU - Cataldo, Maria Adriana

AU - Rosati, Silvia

AU - Zaccaro, Paola

AU - Loffredo, Mariarosaria

AU - Pompa, Maria Grazia

AU - Girardi, Enrico

AU - Scognamiglio, Paola

AU - Ippolito, Giuseppe

AU - Antinori, Andrea

AU - D'Offizi, Gianpiero

AU - Petrosillo, Nicola

AU - Palmieri, Fabrizio

AU - Nurra, Giuseppina

AU - Casalanguida, Annamaria

AU - Ciufoli, Annamaria

AU - Petrecchia, Antonella

AU - Abdeddaim, Amina

AU - Baldini, Franco

AU - Capone, Alessandro

AU - Chinello, Pierangelo

AU - Cicalini, Stefania

AU - Cirino, Luigi

AU - Corpolongo, Angela

AU - Galati, Vincenzo

AU - Ghirga, Piero

AU - Giancola, Letizia

AU - Iacomi, Fabio

AU - Maddaluno, Rita

AU - Mariano, Andrea

AU - Mencarini, Paola

AU - Oliva, Alessandra

AU - Taglietti, Fabrizio

AU - Topino, Simone

AU - Vincenzi, Laura

PY - 2014

Y1 - 2014

N2 - Reduced circulation of hepatitis A virus lead to an increase of susceptible individuals, and outbreaks occurred recently. In Northern Italy an outbreak is ongoing, attributed to a monophyletic genotype IA strain, with mixed frozen berries as probable source. From 01/01/2013 to 07/15/2013, 30 cases were diagnosed at National Institute for Infectious Diseases, Rome, Italy, representing about twice the number of cases in whole 2012. Phylogenetic analysis indicated that most, although not all, infections were attributable to the same monophyletic genotype IA strain identified in the contemporary Northern Italy outbreak. This strain is also very similar to previous isolates from Venezuela.

AB - Reduced circulation of hepatitis A virus lead to an increase of susceptible individuals, and outbreaks occurred recently. In Northern Italy an outbreak is ongoing, attributed to a monophyletic genotype IA strain, with mixed frozen berries as probable source. From 01/01/2013 to 07/15/2013, 30 cases were diagnosed at National Institute for Infectious Diseases, Rome, Italy, representing about twice the number of cases in whole 2012. Phylogenetic analysis indicated that most, although not all, infections were attributable to the same monophyletic genotype IA strain identified in the contemporary Northern Italy outbreak. This strain is also very similar to previous isolates from Venezuela.

KW - Food-borne infections

KW - Hepatitis A

KW - Molecular characterization

KW - Outbreak

KW - Vaccine-preventable diseases

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DO - 10.1016/j.micinf.2014.01.003

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VL - 16

SP - 362

EP - 366

JO - Microbes and Infection

JF - Microbes and Infection

SN - 1286-4579

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