TY - JOUR
T1 - Molecular characterization of integrons in epidemiologically unrelated clinical isolates of Acinetobacter baumannii from Italian Hospitals reveals a limited diversity of gene cassette arrays
AU - Gombac, Francesca
AU - Riccio, Maria Letizia
AU - Rossolini, Maria Gian
AU - Lagatolla, Cristina
AU - Tonin, Enrico
AU - Monti-Bragadin, Carlo
AU - Lavenia, Annamaria
AU - Dolzani, Lucilla
PY - 2002/11
Y1 - 2002/11
N2 - Integron carriage by 36 epidemiologically unrelated Acinetobacter baumannii isolates collected over an 11-year period from patients in six different Italian hospitals was investigated. Sixteen type 1 integron-positive isolates (44%) were found, 13 of which carried the same array of cassettes, i.e., aacC1, orfX, orfX′, and aadA1a. As ribotype analysis of the isolates demonstrated a notable genetic diversity, horizontal transfer of the entire integron structure or ancient acquisition was hypothesized.
AB - Integron carriage by 36 epidemiologically unrelated Acinetobacter baumannii isolates collected over an 11-year period from patients in six different Italian hospitals was investigated. Sixteen type 1 integron-positive isolates (44%) were found, 13 of which carried the same array of cassettes, i.e., aacC1, orfX, orfX′, and aadA1a. As ribotype analysis of the isolates demonstrated a notable genetic diversity, horizontal transfer of the entire integron structure or ancient acquisition was hypothesized.
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U2 - 10.1128/AAC.46.11.3665-3668.2002
DO - 10.1128/AAC.46.11.3665-3668.2002
M3 - Article
C2 - 12384388
AN - SCOPUS:0036838263
VL - 46
SP - 3665
EP - 3668
JO - Antimicrobial Agents and Chemotherapy
JF - Antimicrobial Agents and Chemotherapy
SN - 0066-4804
IS - 11
ER -