Molecular characterization of integrons in epidemiologically unrelated clinical isolates of Acinetobacter baumannii from Italian Hospitals reveals a limited diversity of gene cassette arrays

Francesca Gombac, Maria Letizia Riccio, Maria Gian Rossolini, Cristina Lagatolla, Enrico Tonin, Carlo Monti-Bragadin, Annamaria Lavenia, Lucilla Dolzani

Research output: Contribution to journalArticlepeer-review

Abstract

Integron carriage by 36 epidemiologically unrelated Acinetobacter baumannii isolates collected over an 11-year period from patients in six different Italian hospitals was investigated. Sixteen type 1 integron-positive isolates (44%) were found, 13 of which carried the same array of cassettes, i.e., aacC1, orfX, orfX′, and aadA1a. As ribotype analysis of the isolates demonstrated a notable genetic diversity, horizontal transfer of the entire integron structure or ancient acquisition was hypothesized.

Original languageEnglish
Pages (from-to)3665-3668
Number of pages4
JournalAntimicrobial Agents and Chemotherapy
Volume46
Issue number11
DOIs
Publication statusPublished - Nov 2002

ASJC Scopus subject areas

  • Pharmacology (medical)

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