Molecular characterization of integrons in epidemiologically unrelated clinical isolates of Acinetobacter baumannii from Italian Hospitals reveals a limited diversity of gene cassette arrays

Francesca Gombac; Maria Letizia Riccio; Maria Gian Rossolini; Cristina Lagatolla; Enrico Tonin; Carlo Monti-Bragadin; Annamaria Lavenia; Lucilla Dolzani

doi:10.1128/AAC.46.11.3665-3668.2002

Molecular characterization of integrons in epidemiologically unrelated clinical isolates of Acinetobacter baumannii from Italian Hospitals reveals a limited diversity of gene cassette arrays

Francesca Gombac, Maria Letizia Riccio, Maria Gian Rossolini, Cristina Lagatolla, Enrico Tonin, Carlo Monti-Bragadin, Annamaria Lavenia, Lucilla Dolzani

Fondazione Don Carlo Gnocchi Onlus

Research output: Contribution to journal › Article › peer-review

Abstract

Integron carriage by 36 epidemiologically unrelated Acinetobacter baumannii isolates collected over an 11-year period from patients in six different Italian hospitals was investigated. Sixteen type 1 integron-positive isolates (44%) were found, 13 of which carried the same array of cassettes, i.e., aacC1, orfX, orfX′, and aadA1a. As ribotype analysis of the isolates demonstrated a notable genetic diversity, horizontal transfer of the entire integron structure or ancient acquisition was hypothesized.

Original language	English
Pages (from-to)	3665-3668
Number of pages	4
Journal	Antimicrobial Agents and Chemotherapy
Volume	46
Issue number	11
DOIs	https://doi.org/10.1128/AAC.46.11.3665-3668.2002
Publication status	Published - Nov 2002

ASJC Scopus subject areas

Pharmacology (medical)

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10.1128/AAC.46.11.3665-3668.2002

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Gombac, F., Riccio, M. L., Rossolini, M. G., Lagatolla, C., Tonin, E., Monti-Bragadin, C., Lavenia, A., & Dolzani, L. (2002). Molecular characterization of integrons in epidemiologically unrelated clinical isolates of Acinetobacter baumannii from Italian Hospitals reveals a limited diversity of gene cassette arrays. Antimicrobial Agents and Chemotherapy, 46(11), 3665-3668. https://doi.org/10.1128/AAC.46.11.3665-3668.2002

Molecular characterization of integrons in epidemiologically unrelated clinical isolates of Acinetobacter baumannii from Italian Hospitals reveals a limited diversity of gene cassette arrays. / Gombac, Francesca; Riccio, Maria Letizia; Rossolini, Maria Gian; Lagatolla, Cristina; Tonin, Enrico; Monti-Bragadin, Carlo; Lavenia, Annamaria; Dolzani, Lucilla.

In: Antimicrobial Agents and Chemotherapy, Vol. 46, No. 11, 11.2002, p. 3665-3668.

Research output: Contribution to journal › Article › peer-review

Gombac, F, Riccio, ML, Rossolini, MG, Lagatolla, C, Tonin, E, Monti-Bragadin, C, Lavenia, A & Dolzani, L 2002, 'Molecular characterization of integrons in epidemiologically unrelated clinical isolates of Acinetobacter baumannii from Italian Hospitals reveals a limited diversity of gene cassette arrays', Antimicrobial Agents and Chemotherapy, vol. 46, no. 11, pp. 3665-3668. https://doi.org/10.1128/AAC.46.11.3665-3668.2002

Gombac F, Riccio ML, Rossolini MG, Lagatolla C, Tonin E, Monti-Bragadin C et al. Molecular characterization of integrons in epidemiologically unrelated clinical isolates of Acinetobacter baumannii from Italian Hospitals reveals a limited diversity of gene cassette arrays. Antimicrobial Agents and Chemotherapy. 2002 Nov;46(11):3665-3668. https://doi.org/10.1128/AAC.46.11.3665-3668.2002

Gombac, Francesca ; Riccio, Maria Letizia ; Rossolini, Maria Gian ; Lagatolla, Cristina ; Tonin, Enrico ; Monti-Bragadin, Carlo ; Lavenia, Annamaria ; Dolzani, Lucilla. / Molecular characterization of integrons in epidemiologically unrelated clinical isolates of Acinetobacter baumannii from Italian Hospitals reveals a limited diversity of gene cassette arrays. In: Antimicrobial Agents and Chemotherapy. 2002 ; Vol. 46, No. 11. pp. 3665-3668.

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