Molecular imaging and magnetic resonance imaging in early diagnosis of alzheimer's disease. A literature review

O. Schillaci, L. Travascio, Chiara Bruni, G. Bazzocchi, A. Testa, F. G. Garaci, M. Melis, R. Floris, G. Simonetti

Research output: Contribution to journalArticle

Abstract

Alzheimer's disease (AD), a progressive neurodegenerative disorder, is the most common cause of dementia in the elderly. Magnetic resonance (MR) or computed tomography (CT) imaging is recommended for routine evaluation of dementias. The development of molecular imaging agents and the new techniques of MR for AD are critically important for early diagnosis, neuropathogenesis studies and assessing treatment efficacy in AD. Neuroimaging using nuclear medicine techniques such as SPECT, PET and MR spectroscopy has the potential to characterize the biomarkers for Alzheimer's disease. The present review summarizes the results of radionuclide imaging and MR imaging in AD.

Original languageEnglish
Pages (from-to)755-771
Number of pages17
JournalNeuroradiology Journal
Volume21
Issue number6
Publication statusPublished - Dec 2008

Fingerprint

Molecular Imaging
Early Diagnosis
Alzheimer Disease
Magnetic Resonance Imaging
Magnetic Resonance Spectroscopy
Dementia
Nuclear Medicine
Single-Photon Emission-Computed Tomography
Neuroimaging
Radionuclide Imaging
Neurodegenerative Diseases
Biomarkers
Tomography

Keywords

  • Alzheimer's disease
  • Magnetic resonance
  • Molecular imaging
  • Nuclear medicine
  • PET
  • SPECT

ASJC Scopus subject areas

  • Clinical Neurology
  • Radiology Nuclear Medicine and imaging

Cite this

Schillaci, O., Travascio, L., Bruni, C., Bazzocchi, G., Testa, A., Garaci, F. G., ... Simonetti, G. (2008). Molecular imaging and magnetic resonance imaging in early diagnosis of alzheimer's disease. A literature review. Neuroradiology Journal, 21(6), 755-771.

Molecular imaging and magnetic resonance imaging in early diagnosis of alzheimer's disease. A literature review. / Schillaci, O.; Travascio, L.; Bruni, Chiara; Bazzocchi, G.; Testa, A.; Garaci, F. G.; Melis, M.; Floris, R.; Simonetti, G.

In: Neuroradiology Journal, Vol. 21, No. 6, 12.2008, p. 755-771.

Research output: Contribution to journalArticle

Schillaci, O, Travascio, L, Bruni, C, Bazzocchi, G, Testa, A, Garaci, FG, Melis, M, Floris, R & Simonetti, G 2008, 'Molecular imaging and magnetic resonance imaging in early diagnosis of alzheimer's disease. A literature review', Neuroradiology Journal, vol. 21, no. 6, pp. 755-771.
Schillaci O, Travascio L, Bruni C, Bazzocchi G, Testa A, Garaci FG et al. Molecular imaging and magnetic resonance imaging in early diagnosis of alzheimer's disease. A literature review. Neuroradiology Journal. 2008 Dec;21(6):755-771.
Schillaci, O. ; Travascio, L. ; Bruni, Chiara ; Bazzocchi, G. ; Testa, A. ; Garaci, F. G. ; Melis, M. ; Floris, R. ; Simonetti, G. / Molecular imaging and magnetic resonance imaging in early diagnosis of alzheimer's disease. A literature review. In: Neuroradiology Journal. 2008 ; Vol. 21, No. 6. pp. 755-771.
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