Molecular imaging of atheroslerotic plaque with nuclear medicine techniques (Review)

Orazio Schillaci, Roberta Danieli, Federico Padovano, Angelo Testa, Giovanni Simonetti

Research output: Contribution to journalArticlepeer-review

Abstract

Atherosclerosis is a systemic disease of the vessel wall that mainly affects medium- and large-sized arteries, and accounts for 50% of all deaths in western countries. Imaging of atheromatous plaques has traditionally centered on assessing the degree of luminal narrowing. More recently it has become clear that it is of the utmost importance to identify the vulnerable atherosclerotic plaques responsible for the majority of life-threatening syndromes. Molecular imaging using nuclear medicine techniques such as single-photon emission computed tomography (SPECT) and positron emission tomography (PET), has the potential to characterize the activity of atheromas. In the present review we summarize the results of radionuclide imaging in the detection of vulnerable atherosclerotic lesions.

Original languageEnglish
Pages (from-to)3-7
Number of pages5
JournalInternational Journal of Molecular Medicine
Volume22
Issue number1
Publication statusPublished - Jul 2008

Keywords

  • Atherosclerosis
  • Molecular imaging
  • Nuclear medicine
  • Positron emission tomography
  • Single-photon emission computed tomography

ASJC Scopus subject areas

  • Genetics

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