Molecular Logic: Brief Introduction and Some Philosophical Considerations

Claudio Fuentes Bravo, Patricio Fuentes Bravo

Research output: Chapter in Book/Report/Conference proceedingConference contribution


In the present article a brief historical and systematic introduction to the field of molecular logic are proposed. Some relevant philosophical consequences derived from the technical treatment of this topic are also exposed. These consequences are made explicit in three fundamental questions. Some of the proposed methods for the representation of the intracellular molecular dynamics are also presented and the advantages and limitations that the different methods exhibit when modeling natural biological circuits are evaluated. The Boolean approach to molecular logic is considered with special attention in this article, emphasizing that “logic gates” have proven to be functionally appropriate for analyzing experimental information, however, they present limitations to capture complex biological processes. In relation to this last point, the problem presented by the modeling of continuous variables through discrete systems is studied in depth. It is explained then the need to have adequate logic to the phenomenon and its characteristics.

Original languageEnglish
Title of host publicationMolecular Logic and Computational Synthetic Biology - 1st International Symposium, MLCSB 2018, Revised Selected Papers
EditorsMadalena Chaves, Manuel A. Martins
PublisherSpringer Verlag
Number of pages17
ISBN (Print)9783030194314
Publication statusPublished - Jan 1 2019
Externally publishedYes
Event1st International Symposium on Molecular Logic and Computational Synthetic Biology, MLCSB 2018 - Santiago, Chile
Duration: Dec 17 2018Dec 18 2018

Publication series

NameLecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
Volume11415 LNCS
ISSN (Print)0302-9743
ISSN (Electronic)1611-3349


Conference1st International Symposium on Molecular Logic and Computational Synthetic Biology, MLCSB 2018


  • Boolean approach
  • Logic gates
  • Molecular logic
  • Philosophy

ASJC Scopus subject areas

  • Theoretical Computer Science
  • Computer Science(all)


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