Molecular mechanisms of blood vessel formation

Research output: Contribution to journalArticlepeer-review


The formation of new blood vessels, angiogenesis, is a tightly regulated process. Extracellular angiogenic inducers stimulate the migration and proliferation of endothelial cells, while negative regulators counteract this effect. Changes in the relative balance of inducers and inhibitors activate the 'angiogenic switch', before stabilizer molecules activate the maturation of nascent blood vessels.

Original languageEnglish
Pages (from-to)251-256
Number of pages6
JournalTrends in Biochemical Sciences
Issue number7
Publication statusPublished - Jul 1997

ASJC Scopus subject areas

  • Biochemistry


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