Molecular modelling of HLA-B*35: 132

E. Longhi, P. Crivello, M. Mantovani, S. Frison, K. Fleischhauer, L. Crespiatico, G. Piccolo, F. Poli

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Summary: Here we describe the molecular modelling of the new variant HLA-B*35:132. This allele shows one mismatch with B*35:01:01:01 in exon 3 at position 575 where a T is substituted by a C, which implies an amino acidic change from Leucine to Proline. This seems not to alter the molecular structure and not to compromise the HLA complex and T-cell receptor interaction.

Original languageEnglish
Pages (from-to)195-197
Number of pages3
JournalInternational Journal of Immunogenetics
Volume41
Issue number3
DOIs
Publication statusPublished - 2014

Fingerprint

HLA-B Antigens
T-Cell Antigen Receptor
Molecular Structure
Proline
Leucine
Cell Communication
Exons
Alleles

ASJC Scopus subject areas

  • Genetics
  • Molecular Biology
  • Immunology
  • Genetics(clinical)
  • Medicine(all)

Cite this

Molecular modelling of HLA-B*35 : 132. / Longhi, E.; Crivello, P.; Mantovani, M.; Frison, S.; Fleischhauer, K.; Crespiatico, L.; Piccolo, G.; Poli, F.

In: International Journal of Immunogenetics, Vol. 41, No. 3, 2014, p. 195-197.

Research output: Contribution to journalArticle

Longhi, E. ; Crivello, P. ; Mantovani, M. ; Frison, S. ; Fleischhauer, K. ; Crespiatico, L. ; Piccolo, G. ; Poli, F. / Molecular modelling of HLA-B*35 : 132. In: International Journal of Immunogenetics. 2014 ; Vol. 41, No. 3. pp. 195-197.
@article{f827a28e292a4496aee9ad44937d9475,
title = "Molecular modelling of HLA-B*35: 132",
abstract = "Summary: Here we describe the molecular modelling of the new variant HLA-B*35:132. This allele shows one mismatch with B*35:01:01:01 in exon 3 at position 575 where a T is substituted by a C, which implies an amino acidic change from Leucine to Proline. This seems not to alter the molecular structure and not to compromise the HLA complex and T-cell receptor interaction.",
author = "E. Longhi and P. Crivello and M. Mantovani and S. Frison and K. Fleischhauer and L. Crespiatico and G. Piccolo and F. Poli",
year = "2014",
doi = "10.1111/iji.12105",
language = "English",
volume = "41",
pages = "195--197",
journal = "International Journal of Immunogenetics",
issn = "1744-3121",
publisher = "Wiley-Blackwell",
number = "3",

}

TY - JOUR

T1 - Molecular modelling of HLA-B*35

T2 - 132

AU - Longhi, E.

AU - Crivello, P.

AU - Mantovani, M.

AU - Frison, S.

AU - Fleischhauer, K.

AU - Crespiatico, L.

AU - Piccolo, G.

AU - Poli, F.

PY - 2014

Y1 - 2014

N2 - Summary: Here we describe the molecular modelling of the new variant HLA-B*35:132. This allele shows one mismatch with B*35:01:01:01 in exon 3 at position 575 where a T is substituted by a C, which implies an amino acidic change from Leucine to Proline. This seems not to alter the molecular structure and not to compromise the HLA complex and T-cell receptor interaction.

AB - Summary: Here we describe the molecular modelling of the new variant HLA-B*35:132. This allele shows one mismatch with B*35:01:01:01 in exon 3 at position 575 where a T is substituted by a C, which implies an amino acidic change from Leucine to Proline. This seems not to alter the molecular structure and not to compromise the HLA complex and T-cell receptor interaction.

UR - http://www.scopus.com/inward/record.url?scp=84900454485&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84900454485&partnerID=8YFLogxK

U2 - 10.1111/iji.12105

DO - 10.1111/iji.12105

M3 - Article

C2 - 24401193

AN - SCOPUS:84900454485

VL - 41

SP - 195

EP - 197

JO - International Journal of Immunogenetics

JF - International Journal of Immunogenetics

SN - 1744-3121

IS - 3

ER -