Molecular modelling of HLA-B*35: 132

E. Longhi, P. Crivello, M. Mantovani, S. Frison, K. Fleischhauer, L. Crespiatico, G. Piccolo, F. Poli

Research output: Contribution to journalArticlepeer-review

Abstract

Summary: Here we describe the molecular modelling of the new variant HLA-B*35:132. This allele shows one mismatch with B*35:01:01:01 in exon 3 at position 575 where a T is substituted by a C, which implies an amino acidic change from Leucine to Proline. This seems not to alter the molecular structure and not to compromise the HLA complex and T-cell receptor interaction.

Original languageEnglish
Pages (from-to)195-197
Number of pages3
JournalInternational Journal of Immunogenetics
Volume41
Issue number3
DOIs
Publication statusPublished - 2014

ASJC Scopus subject areas

  • Genetics
  • Molecular Biology
  • Immunology
  • Genetics(clinical)
  • Medicine(all)

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