Molecular profile of liquid biopsies: Next generation biomarkers to improve lung cancer treatment

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Abstract

Molecular profiling of liquid biopsies is now emerging as pivotal for cancer biomarker discovery. The low-invasive nature of the approach used for collecting biospecimens (i.e. blood, urine, saliva, etc.) may allow a widespread application of novel molecular diagnostics based on liquid biopsies. This is relevant, for example, in cancer screening programmes where it is essential to reduce costs and the complexity of screening tests in order to increase study compliance and effectiveness. Here, I discuss recent advances in biomarkers for the early cancer detection and prediction of chemotherapy response based on the molecular profiling of liquid biopsies.

Original languageEnglish
Article number598
Journalecancermedicalscience
Volume9
DOIs
Publication statusPublished - Nov 24 2015

Keywords

  • Biomarkers
  • Circulating biomarkers
  • Circulating tumour DNA
  • Lung cancer
  • MicroRNA

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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