TY - JOUR
T1 - Molecular profiling of chordoma
AU - Scheil-Bertram, Stefanie
AU - Kappler, Roland
AU - Von Baer, Alexandra
AU - Hartwig, Erich
AU - Sarkar, Michael
AU - Serra, Massimo
AU - Brüderlein, Silke
AU - Westhoff, Bettina
AU - Melzner, Ingo
AU - Bassaly, Birgit
AU - Herms, Jochen
AU - Hugo, Heinz Hermann
AU - Schulte, Michael
AU - Möller, Peter
PY - 2014/4
Y1 - 2014/4
N2 - The molecular basis of chordoma is still poorly understood, particularly with respect to differentially expressed genes involved in the primary origin of chordoma. In this study, therefore, we compared the transcriptional expression profile of one sacral chordoma recurrence, two chordoma cell lines (U-CH1 and U-CH2) and one chondrosarcoma cell line (U-CS2) with vertebral disc using a high-density oligonucleotide array. The expression of 65 genes whose mRNA levels differed significantly (p
AB - The molecular basis of chordoma is still poorly understood, particularly with respect to differentially expressed genes involved in the primary origin of chordoma. In this study, therefore, we compared the transcriptional expression profile of one sacral chordoma recurrence, two chordoma cell lines (U-CH1 and U-CH2) and one chondrosarcoma cell line (U-CS2) with vertebral disc using a high-density oligonucleotide array. The expression of 65 genes whose mRNA levels differed significantly (p
KW - Chondrosarcoma
KW - Chordoma
KW - Comparative genomic hybridization
KW - Fluorescence in situ hybridization
KW - GeneChip
UR - http://www.scopus.com/inward/record.url?scp=84894422586&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84894422586&partnerID=8YFLogxK
U2 - 10.3892/ijo.2014.2268
DO - 10.3892/ijo.2014.2268
M3 - Article
C2 - 24452533
AN - SCOPUS:84894422586
VL - 44
SP - 1041
EP - 1055
JO - International Journal of Oncology
JF - International Journal of Oncology
SN - 1019-6439
IS - 4
ER -