Monoamine acid metabolites and cerebrospinal fluid dynamics in normal pressure hydrocephalus: preliminary results

G. Maira; S. R. Bareggi; C. Di Rocco; G. Calderini; P. L. Morselli

Monoamine acid metabolites and cerebrospinal fluid dynamics in normal pressure hydrocephalus: preliminary results

G. Maira, S. R. Bareggi, C. Di Rocco, G. Calderini, P. L. Morselli

Istituto Clinico Humanitas

Research output: Contribution to journal › Article › peer-review

Abstract

Lumbar and ventricular CSF concentration of homovanillic acid (HVA) and 5 hydroxyindole acetic acid (5 HIAA) have been determined in 13 patients admitted to hospital for suspected normal pressure hydrocephalus. Low values of HVA in lumbar CSF were found in all patients with reduced CSF absorption and CSF flow inversion. The HVA lumbar concentration remained low after shunt procedure; it increased if obstruction of the shunt occurred. The ventricular CSF concentration of HVA was normal before surgery; it became higher, in 2 cases, after surgery. No important variations were found in the lumbar and ventricular CSF concentration of 5 HIAA. The possible mechanism and diagnostic value of these findings are discussed.

Original language	English
Pages (from-to)	123-128
Number of pages	6
Journal	Journal of Neurology, Neurosurgery and Psychiatry
Volume	38
Issue number	2
Publication status	Published - 1975

ASJC Scopus subject areas

Neuropsychology and Physiological Psychology
Neuroscience(all)
Psychiatry and Mental health

Access to Document

Fingerprint Dive into the research topics of 'Monoamine acid metabolites and cerebrospinal fluid dynamics in normal pressure hydrocephalus: preliminary results'. Together they form a unique fingerprint.

Cite this

@article{464cbf7f601541208786913bd78cb0fb,

title = "Monoamine acid metabolites and cerebrospinal fluid dynamics in normal pressure hydrocephalus: preliminary results",

abstract = "Lumbar and ventricular CSF concentration of homovanillic acid (HVA) and 5 hydroxyindole acetic acid (5 HIAA) have been determined in 13 patients admitted to hospital for suspected normal pressure hydrocephalus. Low values of HVA in lumbar CSF were found in all patients with reduced CSF absorption and CSF flow inversion. The HVA lumbar concentration remained low after shunt procedure; it increased if obstruction of the shunt occurred. The ventricular CSF concentration of HVA was normal before surgery; it became higher, in 2 cases, after surgery. No important variations were found in the lumbar and ventricular CSF concentration of 5 HIAA. The possible mechanism and diagnostic value of these findings are discussed.",

author = "G. Maira and Bareggi, {S. R.} and {Di Rocco}, C. and G. Calderini and Morselli, {P. L.}",

year = "1975",

language = "English",

volume = "38",

pages = "123--128",

journal = "Journal of Neurology, Neurosurgery and Psychiatry",

issn = "0022-3050",

publisher = "BMJ Publishing Group",

number = "2",

}

TY - JOUR

T1 - Monoamine acid metabolites and cerebrospinal fluid dynamics in normal pressure hydrocephalus

T2 - preliminary results

AU - Maira, G.

AU - Bareggi, S. R.

AU - Di Rocco, C.

AU - Calderini, G.

AU - Morselli, P. L.

PY - 1975

Y1 - 1975

N2 - Lumbar and ventricular CSF concentration of homovanillic acid (HVA) and 5 hydroxyindole acetic acid (5 HIAA) have been determined in 13 patients admitted to hospital for suspected normal pressure hydrocephalus. Low values of HVA in lumbar CSF were found in all patients with reduced CSF absorption and CSF flow inversion. The HVA lumbar concentration remained low after shunt procedure; it increased if obstruction of the shunt occurred. The ventricular CSF concentration of HVA was normal before surgery; it became higher, in 2 cases, after surgery. No important variations were found in the lumbar and ventricular CSF concentration of 5 HIAA. The possible mechanism and diagnostic value of these findings are discussed.

AB - Lumbar and ventricular CSF concentration of homovanillic acid (HVA) and 5 hydroxyindole acetic acid (5 HIAA) have been determined in 13 patients admitted to hospital for suspected normal pressure hydrocephalus. Low values of HVA in lumbar CSF were found in all patients with reduced CSF absorption and CSF flow inversion. The HVA lumbar concentration remained low after shunt procedure; it increased if obstruction of the shunt occurred. The ventricular CSF concentration of HVA was normal before surgery; it became higher, in 2 cases, after surgery. No important variations were found in the lumbar and ventricular CSF concentration of 5 HIAA. The possible mechanism and diagnostic value of these findings are discussed.

UR - http://www.scopus.com/inward/record.url?scp=0016755812&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0016755812&partnerID=8YFLogxK

M3 - Article

C2 - 1151392

AN - SCOPUS:0016755812

VL - 38

SP - 123

EP - 128

JO - Journal of Neurology, Neurosurgery and Psychiatry

JF - Journal of Neurology, Neurosurgery and Psychiatry

SN - 0022-3050

IS - 2

ER -