Monte Carlo characterization of materials for prosthetic implants and dosimetric validation of Pinnacle3 TPS

Francesca Palleri, Fabio Baruffaldi, Anna Lisa Angelini, Andrea Ferri, Emiliano Spezi

Research output: Contribution to journalArticlepeer-review


In external beam radiotherapy the calculation of dose distribution for patients with hip prostheses is critical. Metallic implants not only degrade the image quality but also perturb the dose distribution. Conventional treatment planning systems do not accurately account for high-Z prosthetic implants heterogeneities, especially at interfaces. The materials studied in this work have been chosen on the basis of a statistical investigation on the hip prostheses implanted in 70 medical centres. The first aim of this study is a systematic characterization of materials used for hip prostheses, and it has been provided by BEAMnrc Monte Carlo code. The second aim is to evaluate the capabilities of a specific treatment planning system, Pinnacle3, when dealing with dose calculations in presence of metals, also close to the regions of high-Z gradients. In both cases it has been carried out an accurate comparison versus experimental measurements for two clinical photon beam energies (6 MV and 18 MV) and for two experimental sets-up: metallic cylinders inserted in a water phantom and in a specifically built PMMA slab. Our results show an agreement within 2% between experiments and MC simulations. TPS calculations agree with experiments within 3%.

Original languageEnglish
Pages (from-to)5001-5006
Number of pages6
JournalNuclear Instruments and Methods in Physics Research, Section B: Beam Interactions with Materials and Atoms
Issue number23
Publication statusPublished - Dec 2008


  • BEAMnrc Monte Carlo code
  • Dose calculation
  • Hip prosthesis
  • Treatment planning system

ASJC Scopus subject areas

  • Instrumentation
  • Nuclear and High Energy Physics


Dive into the research topics of 'Monte Carlo characterization of materials for prosthetic implants and dosimetric validation of Pinnacle3 TPS'. Together they form a unique fingerprint.

Cite this