TY - JOUR
T1 - Monte Carlo simulations of an innovative molecular breast imaging system for the small breast cancer diagnosis using GATE
AU - Poma, G. E.
AU - Garibaldi, F.
AU - Giuliani, F.
AU - Insero, T.
AU - Lucentini, M.
AU - Marcucci, A.
AU - Musico, P.
AU - Petta, C.
AU - Santavenere, F.
AU - Sutera, C.
AU - Cisbani, E.
PY - 2019/12/2
Y1 - 2019/12/2
N2 - This paper draws attention to the study of performance of a new Molecular Breast Imaging (MBI) device, whose purpose is the early diagnosis of breast cancer, using Monte Carlo simulations. MBI provides functional and specific information that are more appropriated to dense breasts. Two asymmetric heads with different types of collimators, facing each other in anti-parallel viewing direction, characterize the system. Detectors and phantoms, together with the data taking procedure, are shortly reported. Monte Carlo simulations using the GATE (GEANT4 Application for Tomographic Emission) simulation toolkit have been implemented to evaluate the optimal detector configuration, in terms of sensitivity and spatial resolution, and also to reproduce the real experimental data. The device can be used both in spot compression and in Limited Angle Tomography (LAT); in the latter configuration one detector head with pinhole collimator is able to rotate around the breast in order to diagnose and localized the small tumors.
AB - This paper draws attention to the study of performance of a new Molecular Breast Imaging (MBI) device, whose purpose is the early diagnosis of breast cancer, using Monte Carlo simulations. MBI provides functional and specific information that are more appropriated to dense breasts. Two asymmetric heads with different types of collimators, facing each other in anti-parallel viewing direction, characterize the system. Detectors and phantoms, together with the data taking procedure, are shortly reported. Monte Carlo simulations using the GATE (GEANT4 Application for Tomographic Emission) simulation toolkit have been implemented to evaluate the optimal detector configuration, in terms of sensitivity and spatial resolution, and also to reproduce the real experimental data. The device can be used both in spot compression and in Limited Angle Tomography (LAT); in the latter configuration one detector head with pinhole collimator is able to rotate around the breast in order to diagnose and localized the small tumors.
KW - breast phantoms
KW - gate toolkit
KW - limited angle tomography
KW - Molecular breast imaging
KW - Monte Carlo simulations
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U2 - 10.1080/10420150.2019.1683839
DO - 10.1080/10420150.2019.1683839
M3 - Article
AN - SCOPUS:85077231541
VL - 174
SP - 1008
EP - 1019
JO - Radiation Effects and Defects in Solids
JF - Radiation Effects and Defects in Solids
SN - 1042-0150
IS - 11-12
ER -