TY - JOUR
T1 - Mood disorders and multiple sclerosis
T2 - A study on 65 patients
AU - Salmaggi, A.
AU - Palumbo, R.
AU - Fontanillas, L.
AU - Del Ton, F.
AU - Eoli, M.
AU - Lamantia, L.
AU - Solari, A.
AU - Sghirlanzoni, A.
AU - Milanese, C.
PY - 1997
Y1 - 1997
N2 - Discrepant results are reported in the literature about prevalence of mood disorders in MS; moreover, there are conflicting data about the relationship between presence of mood disorders and cognitive defects and/or disability. We have studied 65 MS patients and 31 patients with polyneuropathies (PNP). Patients have undergone a structured interview based on DSMIV by a trained psychiatrist, with anamnestic evaluation of previous mood disorders, as well as administration of Hamilton and Beck depression rating scales, and complete neurological evaluation with disability scoring according to Kurtzke. In 48 of 65 MS patients, a cognitive evaluation has also been performed (Token test. Attention matrices test, PM47, subtests of logical memory and block design of WAIS). The results confirm the high prevalence of major mood disorders in MS (p=0.001 by logrank test) in comparison with PNP No clearcut relationship has been detetced between presence of mood disorders and cognitive deterioration and/or neurological disability.
AB - Discrepant results are reported in the literature about prevalence of mood disorders in MS; moreover, there are conflicting data about the relationship between presence of mood disorders and cognitive defects and/or disability. We have studied 65 MS patients and 31 patients with polyneuropathies (PNP). Patients have undergone a structured interview based on DSMIV by a trained psychiatrist, with anamnestic evaluation of previous mood disorders, as well as administration of Hamilton and Beck depression rating scales, and complete neurological evaluation with disability scoring according to Kurtzke. In 48 of 65 MS patients, a cognitive evaluation has also been performed (Token test. Attention matrices test, PM47, subtests of logical memory and block design of WAIS). The results confirm the high prevalence of major mood disorders in MS (p=0.001 by logrank test) in comparison with PNP No clearcut relationship has been detetced between presence of mood disorders and cognitive deterioration and/or neurological disability.
UR - http://www.scopus.com/inward/record.url?scp=33746340316&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=33746340316&partnerID=8YFLogxK
M3 - Article
AN - SCOPUS:33746340316
VL - 18
SP - 76
JO - Italian Journal of Neurological Sciences
JF - Italian Journal of Neurological Sciences
SN - 0392-0461
IS - 4
ER -