More Extensive Lymph Node Dissection Improves Survival Benefit of Radical Cystectomy in Metastatic Urothelial Carcinoma of the Bladder

Elio Mazzone, Felix Preisser, Sebastiano Nazzani, Zhe Tian, Nicola Fossati, Giorgio Gandaglia, Andrea Gallina, Denis Soulieres, Derya Tilki, Francesco Montorsi, Shahrokh F. Shariat, Fred Saad, Alberto Briganti, Pierre I. Karakiewicz

Research output: Contribution to journalArticle


We studied the effect of radical cystectomy (RC) on cancer-specific mortality and overall mortality in contemporary metastatic urothelial carcinoma of the bladder (mUCB) patients. Additionally, we analyzed the role of lymph node dissection (LND) in the same context. We found that RC plus extended LND is associated with better survival outcomes relative to no local treatment in mUCB patients.

Original languageEnglish
Pages (from-to)105-113.e2
JournalClinical Genitourinary Cancer
Issue number2
Publication statusPublished - Apr 2019



  • Cancer-specific mortality
  • Metastatic bladder cancer
  • Number of removed nodes
  • Propensity-score matching
  • SEER Program

ASJC Scopus subject areas

  • Oncology
  • Urology

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