After rapidly illustrating the decisive contribution recently made by morphological studies to an improved knowledge of the physiopathology of the pancreatic islets, the Authors describe in detail the morphological characteristics of the three insular cell types nowadays known best, that is, of cells A, B and D, which can be deduced from the most recent observations in light microscopy, dark field and electron microscopy, and from histochemical, enzyme-histochemical and immunohistochemical studies. On the basis of the results obtained from the morphological studies, they turn to discussion of the functional part played by the single cytotypes and their role in the tumoral pathology of the pancreatic islets.
ASJC Scopus subject areas
- Endocrinology, Diabetes and Metabolism
- Internal Medicine