Abstract
We have examined the addition of Escherichia coli to the diet at day 0 of adult life of females from two Oregon R Drosophila melanogaster strains, selected for different longevities: a short-life with an average adult life span of 10 days and a long-life standard R strain with an average adult life span of 50 days. The addition of bacteria to the diet significantly prolonged the fly longevity in both strains and affected the structure and histochemical reactivity of the fat body. The increased survival was characterized by great amount of glycogen accumulated in fat body cells from both strains. In aged control animals, fed with standard diet, lipid droplets were seen to be stored in fat body of short-lived, but not long-lived, flies. On the whole, our data indicate that exogenous bacteria are able to extend the survival of Drosophila females, and suggest that such a beneficial effect can be mediated, at least in part, by the fat body cells that likely play a role in modulating the accumulation and mobilization of reserve stores to ensure lifelong energy homeostasis..
| Original language | English |
|---|---|
| Pages (from-to) | 243-251 |
| Number of pages | 9 |
| Journal | Journal of Molecular Histology |
| Volume | 43 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - Apr 2012 |
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Keywords
- Drosophila melanogaster
- Escherichia coli
- Fat body
- Histochemistry
- Longevity
- Morphology
ASJC Scopus subject areas
- Cell Biology
- Histology
- Physiology
Cite this
Morpho-functional changes of fat body in bacteria fed Drosophila melanogaster strains. / Franchini, Antonella; Mandrioli, Mauro; Franceschi, Claudio; Ottaviani, Enzo.
In: Journal of Molecular Histology, Vol. 43, No. 2, 04.2012, p. 243-251.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Morpho-functional changes of fat body in bacteria fed Drosophila melanogaster strains
AU - Franchini, Antonella
AU - Mandrioli, Mauro
AU - Franceschi, Claudio
AU - Ottaviani, Enzo
PY - 2012/4
Y1 - 2012/4
N2 - We have examined the addition of Escherichia coli to the diet at day 0 of adult life of females from two Oregon R Drosophila melanogaster strains, selected for different longevities: a short-life with an average adult life span of 10 days and a long-life standard R strain with an average adult life span of 50 days. The addition of bacteria to the diet significantly prolonged the fly longevity in both strains and affected the structure and histochemical reactivity of the fat body. The increased survival was characterized by great amount of glycogen accumulated in fat body cells from both strains. In aged control animals, fed with standard diet, lipid droplets were seen to be stored in fat body of short-lived, but not long-lived, flies. On the whole, our data indicate that exogenous bacteria are able to extend the survival of Drosophila females, and suggest that such a beneficial effect can be mediated, at least in part, by the fat body cells that likely play a role in modulating the accumulation and mobilization of reserve stores to ensure lifelong energy homeostasis..
AB - We have examined the addition of Escherichia coli to the diet at day 0 of adult life of females from two Oregon R Drosophila melanogaster strains, selected for different longevities: a short-life with an average adult life span of 10 days and a long-life standard R strain with an average adult life span of 50 days. The addition of bacteria to the diet significantly prolonged the fly longevity in both strains and affected the structure and histochemical reactivity of the fat body. The increased survival was characterized by great amount of glycogen accumulated in fat body cells from both strains. In aged control animals, fed with standard diet, lipid droplets were seen to be stored in fat body of short-lived, but not long-lived, flies. On the whole, our data indicate that exogenous bacteria are able to extend the survival of Drosophila females, and suggest that such a beneficial effect can be mediated, at least in part, by the fat body cells that likely play a role in modulating the accumulation and mobilization of reserve stores to ensure lifelong energy homeostasis..
KW - Drosophila melanogaster
KW - Escherichia coli
KW - Fat body
KW - Histochemistry
KW - Longevity
KW - Morphology
UR - http://www.scopus.com/inward/record.url?scp=84861097313&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84861097313&partnerID=8YFLogxK
U2 - 10.1007/s10735-011-9382-y
DO - 10.1007/s10735-011-9382-y
M3 - Article
C2 - 22179854
AN - SCOPUS:84861097313
VL - 43
SP - 243
EP - 251
JO - Journal of Molecular Histology
JF - Journal of Molecular Histology
SN - 1567-2379
IS - 2
ER -