Morpho-functional changes of fat body in bacteria fed Drosophila melanogaster strains

Antonella Franchini, Mauro Mandrioli, Claudio Franceschi, Enzo Ottaviani

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

We have examined the addition of Escherichia coli to the diet at day 0 of adult life of females from two Oregon R Drosophila melanogaster strains, selected for different longevities: a short-life with an average adult life span of 10 days and a long-life standard R strain with an average adult life span of 50 days. The addition of bacteria to the diet significantly prolonged the fly longevity in both strains and affected the structure and histochemical reactivity of the fat body. The increased survival was characterized by great amount of glycogen accumulated in fat body cells from both strains. In aged control animals, fed with standard diet, lipid droplets were seen to be stored in fat body of short-lived, but not long-lived, flies. On the whole, our data indicate that exogenous bacteria are able to extend the survival of Drosophila females, and suggest that such a beneficial effect can be mediated, at least in part, by the fat body cells that likely play a role in modulating the accumulation and mobilization of reserve stores to ensure lifelong energy homeostasis..

Original languageEnglish
Pages (from-to)243-251
Number of pages9
JournalJournal of Molecular Histology
Volume43
Issue number2
DOIs
Publication statusPublished - Apr 2012

Fingerprint

Fat Body
Drosophila melanogaster
Bacteria
Diet
Adipocytes
Diptera
Glycogen
Drosophila
Homeostasis
Escherichia coli

Keywords

  • Drosophila melanogaster
  • Escherichia coli
  • Fat body
  • Histochemistry
  • Longevity
  • Morphology

ASJC Scopus subject areas

  • Cell Biology
  • Histology
  • Physiology

Cite this

Morpho-functional changes of fat body in bacteria fed Drosophila melanogaster strains. / Franchini, Antonella; Mandrioli, Mauro; Franceschi, Claudio; Ottaviani, Enzo.

In: Journal of Molecular Histology, Vol. 43, No. 2, 04.2012, p. 243-251.

Research output: Contribution to journalArticle

Franchini, Antonella ; Mandrioli, Mauro ; Franceschi, Claudio ; Ottaviani, Enzo. / Morpho-functional changes of fat body in bacteria fed Drosophila melanogaster strains. In: Journal of Molecular Histology. 2012 ; Vol. 43, No. 2. pp. 243-251.
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