Abstract
Background: To correlate patterns in short-wavelength (SW) and near-infrared (NIR) fundus autofluorescence (FAF) with morpho-functional outcomes in eyes affected by Stargardt disease. Methods: Fifty-four eyes of 27 patients were prospectively enrolled. All patients underwent a complete ophthalmologic examination including SW-FAF, NIR-FAF, microperimetry and spectral-domain optical coherence tomography (SD-OCT). The main outcome measures were identification of a correlation between NIR-FAF and SW-FAF patterns within the foveal region and best corrected visual acuity (BCVA) values. Secondary outcome measures were correlation of FAF patterns with SD-OCT findings and retinal sensitivity on microperimetry. Results: Eyes showing a pattern of foveal hyper-FAF on NIR-FAF had a higher BCVA than eyes with a reduced FAF signal (0.44±0.23 LogMAR vs 1.08±0.19, p
| Original language | English |
|---|---|
| Pages (from-to) | 1354-1359 |
| Number of pages | 6 |
| Journal | British Journal of Ophthalmology |
| Volume | 99 |
| Issue number | 10 |
| DOIs | |
| Publication status | Published - Oct 1 2015 |
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ASJC Scopus subject areas
- Ophthalmology
- Sensory Systems
- Cellular and Molecular Neuroscience
- Medicine(all)
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Morpho-functional correlation of fundus autofluorescence in Stargardt disease. / Parodi, Maurizio Battaglia; Iacono, Pierluigi; Triolo, Giacinto; La Spina, Carlo; Zucchiatti, Ilaria; Cicinelli, Maria Vittoria; Borrelli, Enrico; Pia Manitto, Maria; Martina, Elisabetta; Bandello, Francesco.
In: British Journal of Ophthalmology, Vol. 99, No. 10, 01.10.2015, p. 1354-1359.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Morpho-functional correlation of fundus autofluorescence in Stargardt disease
AU - Parodi, Maurizio Battaglia
AU - Iacono, Pierluigi
AU - Triolo, Giacinto
AU - La Spina, Carlo
AU - Zucchiatti, Ilaria
AU - Cicinelli, Maria Vittoria
AU - Borrelli, Enrico
AU - Pia Manitto, Maria
AU - Martina, Elisabetta
AU - Bandello, Francesco
PY - 2015/10/1
Y1 - 2015/10/1
N2 - Background: To correlate patterns in short-wavelength (SW) and near-infrared (NIR) fundus autofluorescence (FAF) with morpho-functional outcomes in eyes affected by Stargardt disease. Methods: Fifty-four eyes of 27 patients were prospectively enrolled. All patients underwent a complete ophthalmologic examination including SW-FAF, NIR-FAF, microperimetry and spectral-domain optical coherence tomography (SD-OCT). The main outcome measures were identification of a correlation between NIR-FAF and SW-FAF patterns within the foveal region and best corrected visual acuity (BCVA) values. Secondary outcome measures were correlation of FAF patterns with SD-OCT findings and retinal sensitivity on microperimetry. Results: Eyes showing a pattern of foveal hyper-FAF on NIR-FAF had a higher BCVA than eyes with a reduced FAF signal (0.44±0.23 LogMAR vs 1.08±0.19, p
AB - Background: To correlate patterns in short-wavelength (SW) and near-infrared (NIR) fundus autofluorescence (FAF) with morpho-functional outcomes in eyes affected by Stargardt disease. Methods: Fifty-four eyes of 27 patients were prospectively enrolled. All patients underwent a complete ophthalmologic examination including SW-FAF, NIR-FAF, microperimetry and spectral-domain optical coherence tomography (SD-OCT). The main outcome measures were identification of a correlation between NIR-FAF and SW-FAF patterns within the foveal region and best corrected visual acuity (BCVA) values. Secondary outcome measures were correlation of FAF patterns with SD-OCT findings and retinal sensitivity on microperimetry. Results: Eyes showing a pattern of foveal hyper-FAF on NIR-FAF had a higher BCVA than eyes with a reduced FAF signal (0.44±0.23 LogMAR vs 1.08±0.19, p
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UR - http://www.scopus.com/inward/citedby.url?scp=84942368540&partnerID=8YFLogxK
U2 - 10.1136/bjophthalmol-2014-306237
DO - 10.1136/bjophthalmol-2014-306237
M3 - Article
C2 - 25837607
AN - SCOPUS:84942368540
VL - 99
SP - 1354
EP - 1359
JO - British Journal of Ophthalmology
JF - British Journal of Ophthalmology
SN - 0007-1161
IS - 10
ER -