Diagnostica per immagini morfo-funzionale nella valutazione del miocardio vitale in pazienti con cardiopatia ischemica. Correlazioni tra perfusione miocardica e funzione regionale del ventricolo sinistro.

Translated title of the contribution: Morpho-functional diagnostic imaging in the assessment of viable myocardium in patients with ischemic heart disease. Correlations between myocardial perfusion and regional function of the left ventricle

A. Cuocolo, L. Pace, S. Maurea, A. Nappi, E. Nicolai, M. Imbriaco, P. Sullo, S. Cardei, M. Salvatore

Research output: Contribution to journalArticle

Abstract

Forty patients (38 men and 2 women, mean age 56 +/- 9 years) with angiographic evidence of coronary artery disease underwent 201Thallium myocardial scintigraphy and two-dimensional echocardiography. 201Thallium uptake and echocardiographic regional ventricular function were studied in corresponding myocardial segments. On exercise-redistribution 201Thallium imaging, 308 segments (51% of the total) had normal Thallium uptake, 48 (8%) exhibited reversible defects and 244 (41%) irreversible defects. Of the latter 244 segments with irreversible defects, 114 (47%) exhibited increased tracer uptake (Re+) and 130 (53%) remained unchanged (Re-) after 201Thallium reinjection at rest. Regional ventricular function was significantly better in the segments with normal Thallium uptake than in the segments with reversible or irreversible defects (p <0.001). Furthermore, the segments with irreversible defects Re- had impaired regional function compared to the segments with irreversible defects Re+ (p <0.001). Coronary artery stenosis was significantly more severe in the segments with irreversible defects Re- (93 +/- 16%) than in those with reversible defects (81 +/- 20%) and with irreversible Re+ defects (80 +/- 20%) (both p <0.001). In conclusion, in coronary artery disease patients, exercise-redistribution 201Thallium cardiac imaging with reinjection at rest can identify severely ischemic but still viable myocardium and may be particularly useful in the prognosis of such patients.

Original languageItalian
Pages (from-to)870-875
Number of pages6
JournalRadiologia Medica
Volume89
Issue number6
Publication statusPublished - Jun 1995

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ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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