Morpho-structural investigations of biomaterials for biocidal activity

A. Pugnaloni, F. Gabbanelli, M. Mattioli-Belmonte, A. Delfino, G. Biagini, M. G. Tucci, G. Ricotti, F. Orlando, C. Viticchi, M. Fini

Research output: Contribution to journalArticle

Abstract

A new wound dressing made of gelatin and Ag, was evaluated for the management of tissue reconstitution in rats. The gelatin-based dressing, with metabolic stimulation properties that favored the recovery of the skin was made of stiff sheets to supply the repairing tissue with mechanical support. The gelatin sheets enhanced the development of collagen fibers and subsequently cell proliferation at the level of stromal and vascular elements. A protocol based on the utilization of natural biomaterials in the presence of low concentrations of a biocidal was proposed which could control microbiocidal activities principally in burned and debilitated patients.

Original languageEnglish
Pages (from-to)451-462
Number of pages12
JournalJournal of Bioactive and Compatible Polymers
Volume17
Issue number6
DOIs
Publication statusPublished - Nov 2002

Keywords

  • Biocides
  • Biomaterials
  • Collagen
  • Cutaneous repair
  • Gelatin
  • Wound dressing

ASJC Scopus subject areas

  • Biotechnology
  • Biomaterials
  • Polymers and Plastics
  • Materials Chemistry

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  • Cite this

    Pugnaloni, A., Gabbanelli, F., Mattioli-Belmonte, M., Delfino, A., Biagini, G., Tucci, M. G., Ricotti, G., Orlando, F., Viticchi, C., & Fini, M. (2002). Morpho-structural investigations of biomaterials for biocidal activity. Journal of Bioactive and Compatible Polymers, 17(6), 451-462. https://doi.org/10.1177/088391102031641