Morphogénèse des cellules erythropoïètiques à deux noyaux par I'action des rayons X

E. G. Rondanelli, E. Magliulo, V. Vannini, G. Gerna

Research output: Contribution to journalArticle

Abstract

In irradiated hemopoietic tissues in vitro the formation of iso- and aniso-binu-cleated erythropoietic cells is caused by the failure of cytoplasm to divide and separate daughter nuclei reconstituted by the chromosomes of bi-pluri-ceiitric inetaphases and bi-pluri-polar ana-telophases. The size of the two nuclei, and the resulting iso- or aniso-nuclcarity, is in relation with the number of chromosomes from which each nucleus was reconstituted. Binuclcatcd cells may also result by fusion of the cytoplasm, of two neighbouring cells previously issued from a normal mitosis. Intrinsic mechanisms of the formation of binucleated cells are discussed.

Original languageEnglish
Pages (from-to)97-109
Number of pages13
JournalActa Haematologica
Volume33
Issue number2
DOIs
Publication statusPublished - 1965

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Cytoplasm
Chromosomes
Telophase
Mitosis
In Vitro Techniques

ASJC Scopus subject areas

  • Hematology

Cite this

Morphogénèse des cellules erythropoïètiques à deux noyaux par I'action des rayons X. / Rondanelli, E. G.; Magliulo, E.; Vannini, V.; Gerna, G.

In: Acta Haematologica, Vol. 33, No. 2, 1965, p. 97-109.

Research output: Contribution to journalArticle

Rondanelli, E. G. ; Magliulo, E. ; Vannini, V. ; Gerna, G. / Morphogénèse des cellules erythropoïètiques à deux noyaux par I'action des rayons X. In: Acta Haematologica. 1965 ; Vol. 33, No. 2. pp. 97-109.
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