Morphologic changes in the microcirculation induced by chronic smoking habit: a videocapillaroscopic study on the human labial mucosa.

Raffaele Molino Lova, Benedetta Miniati, Claudio Macchi, Massimo Gulisano, Gherardo Gheri, Claudio Catini, Andrea A. Conti, Gian Franco Gensini

Research output: Contribution to journalArticlepeer-review

Abstract

BACKGROUND: Cigarette smoking has been identified as a major risk factor for cardiovascular and pulmonary diseases. Although an impressive literature does exist on the subject, no evidence is available on morphologic changes induced with chronic smoking habit in the human microcirculation. SUBJECTS AND METHODS: One hundred healthy subjects, 50 smokers and 50 nonsmokers, underwent videocapillaroscopy of the labial mucosa. For each subject, the caliber of capillary loops, the number of visible capillary loops, the background optical transmittance, the tortuousness of capillary loops, the presence of microaneurysms, the presence of microhemorrhages, and the cumulative smoking habit (pack-year index) were noted. RESULTS: Smokers had a lower caliber of capillary loops (P

Original languageEnglish
Pages (from-to)658
Number of pages1
JournalAmerican Heart Journal
Volume143
Issue number4
Publication statusPublished - Apr 2002

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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