Morphological and cytochemical studies of circulating Hodgkin's and Reed-Sternberg cells

A. Malfitano, M. Cazzola, P. Cavalli, P. G. Gobbi, M. Gorini, E. Ascari, S. Perugini

Research output: Contribution to journalArticlepeer-review

Abstract

Morphological and cytochemical studies of circulating neoplastic cells were carried out in a patient who presented a preterminal leukaemic phase of Hodgkin's disease (HD). Three types of abnormal cells were found in the peripheral blood: abnormal mononuclear cells, Hodgkin's cells and Reed-Sternberg cells. All neoplastic cells were cytochemically negative to Sudan black B, peroxidase and alkaline phosphatase. Some neoplastic cells were positive to PAS and all were positive to acid phosphatase, α-naphthylacetate esterase and β-glucuronidase. The origin of the neoplastic population in HD is discussed.

Original languageEnglish
Pages (from-to)101-107
Number of pages7
JournalBasic and Applied Histochemistry
Volume24
Issue number2
Publication statusPublished - 1980

ASJC Scopus subject areas

  • Anatomy

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