Morphological and cytochemical studies of circulating neoplastic cells were carried out in a patient who presented a preterminal leukaemic phase of Hodgkin's disease (HD). Three types of abnormal cells were found in the peripheral blood: abnormal mononuclear cells, Hodgkin's cells and Reed-Sternberg cells. All neoplastic cells were cytochemically negative to Sudan black B, peroxidase and alkaline phosphatase. Some neoplastic cells were positive to PAS and all were positive to acid phosphatase, α-naphthylacetate esterase and β-glucuronidase. The origin of the neoplastic population in HD is discussed.
|Number of pages||7|
|Journal||Basic and Applied Histochemistry|
|Publication status||Published - 1980|
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