Morphological and functional MR imaging of Lhermitte-Duclos disease with pathology correlate

A. Cianfoni, M. Wintermark, F. Piludu, Q. G. D'Alessandris, L. Lauriola, M. Visocchi, C. Colosimo

Research output: Contribution to journalArticle

Abstract

Lhermitte-Duclos disease (LDD) is a rare benign lesion of uncertain pathogenesis characterised by distortion of the normal cerebellar laminar cytoarchitecture. We report a case of LDD thoroughly characterized by advanced magnetic resonance imaging techniques, with diffusion-weighted, perfusion-weighted and post-gadolinium sequences. Imaging showed restricted diffusion consistent with high cellularity, high degree of vascularity and preserved blood-brain barrier permeability, correlating with pathology.

Original languageEnglish
Pages (from-to)297-300
Number of pages4
JournalJournal of Neuroradiology
Volume35
Issue number5
DOIs
Publication statusPublished - Dec 2008

Fingerprint

Multiple Hamartoma Syndrome
Pathology
Gadolinium
Blood-Brain Barrier
Permeability
Perfusion
Magnetic Resonance Imaging

Keywords

  • Diffusion-weighted imaging
  • Gadolinium
  • Lhermitte-Duclos disease
  • MRI
  • Perfusion

ASJC Scopus subject areas

  • Clinical Neurology
  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

Cite this

Cianfoni, A., Wintermark, M., Piludu, F., D'Alessandris, Q. G., Lauriola, L., Visocchi, M., & Colosimo, C. (2008). Morphological and functional MR imaging of Lhermitte-Duclos disease with pathology correlate. Journal of Neuroradiology, 35(5), 297-300. https://doi.org/10.1016/j.neurad.2008.05.002

Morphological and functional MR imaging of Lhermitte-Duclos disease with pathology correlate. / Cianfoni, A.; Wintermark, M.; Piludu, F.; D'Alessandris, Q. G.; Lauriola, L.; Visocchi, M.; Colosimo, C.

In: Journal of Neuroradiology, Vol. 35, No. 5, 12.2008, p. 297-300.

Research output: Contribution to journalArticle

Cianfoni, A, Wintermark, M, Piludu, F, D'Alessandris, QG, Lauriola, L, Visocchi, M & Colosimo, C 2008, 'Morphological and functional MR imaging of Lhermitte-Duclos disease with pathology correlate', Journal of Neuroradiology, vol. 35, no. 5, pp. 297-300. https://doi.org/10.1016/j.neurad.2008.05.002
Cianfoni A, Wintermark M, Piludu F, D'Alessandris QG, Lauriola L, Visocchi M et al. Morphological and functional MR imaging of Lhermitte-Duclos disease with pathology correlate. Journal of Neuroradiology. 2008 Dec;35(5):297-300. https://doi.org/10.1016/j.neurad.2008.05.002
Cianfoni, A. ; Wintermark, M. ; Piludu, F. ; D'Alessandris, Q. G. ; Lauriola, L. ; Visocchi, M. ; Colosimo, C. / Morphological and functional MR imaging of Lhermitte-Duclos disease with pathology correlate. In: Journal of Neuroradiology. 2008 ; Vol. 35, No. 5. pp. 297-300.
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