Morphology and nuclear contents in IVF embryos

L. Dalpra, M. G. Tibiletti, C. Cristiani, G. Ragni, P. G. Crosignani

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Human pre-embryos, at 2-8 cells, with different morphology have been examined for chromosome constitution. Concerning the informative pre-embryos (23/65), 11 showed a normal karyotype and in 12 an abnormal karyotype was observed; there was not a complete correspondence between pronucleation and chromosome set. Also in the interphasic pre-embryos the presence of chromatin masses at different sizes was revealed. The observation of polyploid and/or polynucleated blastomeres can suggest a failure of synchronization between cytoplasmatic and nuclear division. Mosaicism, polyploidy and polynucleation are phenomena that could be caused by in vitro culture conditions or dependent upon the genetic anomaly of the zygote.

Original languageEnglish
Pages (from-to)100-106
Number of pages7
JournalAnnales de Genetique
Volume36
Issue number2
Publication statusPublished - 1993

Fingerprint

Polyploidy
Embryonic Structures
Chromosomes
Cell Nucleus Division
Abnormal Karyotype
Blastomeres
Mosaicism
Zygote
Constitution and Bylaws
Karyotype
Chromatin
Observation
In Vitro Techniques

Keywords

  • chromosome
  • in vitro fertilization
  • pre-embryo

ASJC Scopus subject areas

  • Genetics

Cite this

Dalpra, L., Tibiletti, M. G., Cristiani, C., Ragni, G., & Crosignani, P. G. (1993). Morphology and nuclear contents in IVF embryos. Annales de Genetique, 36(2), 100-106.

Morphology and nuclear contents in IVF embryos. / Dalpra, L.; Tibiletti, M. G.; Cristiani, C.; Ragni, G.; Crosignani, P. G.

In: Annales de Genetique, Vol. 36, No. 2, 1993, p. 100-106.

Research output: Contribution to journalArticle

Dalpra, L, Tibiletti, MG, Cristiani, C, Ragni, G & Crosignani, PG 1993, 'Morphology and nuclear contents in IVF embryos', Annales de Genetique, vol. 36, no. 2, pp. 100-106.
Dalpra L, Tibiletti MG, Cristiani C, Ragni G, Crosignani PG. Morphology and nuclear contents in IVF embryos. Annales de Genetique. 1993;36(2):100-106.
Dalpra, L. ; Tibiletti, M. G. ; Cristiani, C. ; Ragni, G. ; Crosignani, P. G. / Morphology and nuclear contents in IVF embryos. In: Annales de Genetique. 1993 ; Vol. 36, No. 2. pp. 100-106.
@article{fcf9e1b2d3b941d2961d67da978f6142,
title = "Morphology and nuclear contents in IVF embryos",
abstract = "Human pre-embryos, at 2-8 cells, with different morphology have been examined for chromosome constitution. Concerning the informative pre-embryos (23/65), 11 showed a normal karyotype and in 12 an abnormal karyotype was observed; there was not a complete correspondence between pronucleation and chromosome set. Also in the interphasic pre-embryos the presence of chromatin masses at different sizes was revealed. The observation of polyploid and/or polynucleated blastomeres can suggest a failure of synchronization between cytoplasmatic and nuclear division. Mosaicism, polyploidy and polynucleation are phenomena that could be caused by in vitro culture conditions or dependent upon the genetic anomaly of the zygote.",
keywords = "chromosome, in vitro fertilization, pre-embryo",
author = "L. Dalpra and Tibiletti, {M. G.} and C. Cristiani and G. Ragni and Crosignani, {P. G.}",
year = "1993",
language = "English",
volume = "36",
pages = "100--106",
journal = "Annales de Genetique",
issn = "0003-3995",
publisher = "Elsevier BV",
number = "2",

}

TY - JOUR

T1 - Morphology and nuclear contents in IVF embryos

AU - Dalpra, L.

AU - Tibiletti, M. G.

AU - Cristiani, C.

AU - Ragni, G.

AU - Crosignani, P. G.

PY - 1993

Y1 - 1993

N2 - Human pre-embryos, at 2-8 cells, with different morphology have been examined for chromosome constitution. Concerning the informative pre-embryos (23/65), 11 showed a normal karyotype and in 12 an abnormal karyotype was observed; there was not a complete correspondence between pronucleation and chromosome set. Also in the interphasic pre-embryos the presence of chromatin masses at different sizes was revealed. The observation of polyploid and/or polynucleated blastomeres can suggest a failure of synchronization between cytoplasmatic and nuclear division. Mosaicism, polyploidy and polynucleation are phenomena that could be caused by in vitro culture conditions or dependent upon the genetic anomaly of the zygote.

AB - Human pre-embryos, at 2-8 cells, with different morphology have been examined for chromosome constitution. Concerning the informative pre-embryos (23/65), 11 showed a normal karyotype and in 12 an abnormal karyotype was observed; there was not a complete correspondence between pronucleation and chromosome set. Also in the interphasic pre-embryos the presence of chromatin masses at different sizes was revealed. The observation of polyploid and/or polynucleated blastomeres can suggest a failure of synchronization between cytoplasmatic and nuclear division. Mosaicism, polyploidy and polynucleation are phenomena that could be caused by in vitro culture conditions or dependent upon the genetic anomaly of the zygote.

KW - chromosome

KW - in vitro fertilization

KW - pre-embryo

UR - http://www.scopus.com/inward/record.url?scp=0027272924&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0027272924&partnerID=8YFLogxK

M3 - Article

VL - 36

SP - 100

EP - 106

JO - Annales de Genetique

JF - Annales de Genetique

SN - 0003-3995

IS - 2

ER -