Abstract
A historical cohort mortality study conducted among 515 silicotic subjects revealed higher than expected risks for all causes [standardized mortality ratio (SMR) 1.89], respiratory tract diseases (SMR 8.89), silicotuberculosis (SMR 27.00), respiratory tract cancers (SMR 3.14), and lung cancer (SMR 3.50). Mortality from cardiovascular diseases was lower than that expected (SMR 0.51). Lung cancer risk increased with duration of occupational exposure (SMR 2.80, 2.99, and 5.02 for 14, 15-29, and 30 years of employment, respectively). Lung cancer risk was higher for the silicotics without tuberculosis (SMR 3.72) than for those with tuberculosis (SMR 2.83). Indirect adjustment for smoking habits, including number of cigarettes smoked per day, showed that smoking would have been responsible for a maximum risk of 1.77. Thus smoking may have explained 50% of the observed excess mortality from lung cancer.
| Original language | English |
|---|---|
| Pages (from-to) | 77-80 |
| Number of pages | 4 |
| Journal | Scandinavian Journal of Work, Environment and Health |
| Volume | 21 |
| Issue number | SUPPL. 2 |
| Publication status | Published - 1995 |
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Keywords
- Epidemiology
- Italian silicotics
- Pulmonary tuberculosis
- Respiratory tract cancer
- Smoking
ASJC Scopus subject areas
- Public Health, Environmental and Occupational Health
- Toxicology
- Geography, Planning and Development
- Health, Toxicology and Mutagenesis
Cite this
Mortality among silicotics in Genoa, Italy, from 1961 to 1987. / Merlo, F.; Fontana, L.; Reggiardo, G.; Ceppi, M.; Barisone, G.; Garrone, E.; Doria, M.
In: Scandinavian Journal of Work, Environment and Health, Vol. 21, No. SUPPL. 2, 1995, p. 77-80.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Mortality among silicotics in Genoa, Italy, from 1961 to 1987
AU - Merlo, F.
AU - Fontana, L.
AU - Reggiardo, G.
AU - Ceppi, M.
AU - Barisone, G.
AU - Garrone, E.
AU - Doria, M.
PY - 1995
Y1 - 1995
N2 - A historical cohort mortality study conducted among 515 silicotic subjects revealed higher than expected risks for all causes [standardized mortality ratio (SMR) 1.89], respiratory tract diseases (SMR 8.89), silicotuberculosis (SMR 27.00), respiratory tract cancers (SMR 3.14), and lung cancer (SMR 3.50). Mortality from cardiovascular diseases was lower than that expected (SMR 0.51). Lung cancer risk increased with duration of occupational exposure (SMR 2.80, 2.99, and 5.02 for 14, 15-29, and 30 years of employment, respectively). Lung cancer risk was higher for the silicotics without tuberculosis (SMR 3.72) than for those with tuberculosis (SMR 2.83). Indirect adjustment for smoking habits, including number of cigarettes smoked per day, showed that smoking would have been responsible for a maximum risk of 1.77. Thus smoking may have explained 50% of the observed excess mortality from lung cancer.
AB - A historical cohort mortality study conducted among 515 silicotic subjects revealed higher than expected risks for all causes [standardized mortality ratio (SMR) 1.89], respiratory tract diseases (SMR 8.89), silicotuberculosis (SMR 27.00), respiratory tract cancers (SMR 3.14), and lung cancer (SMR 3.50). Mortality from cardiovascular diseases was lower than that expected (SMR 0.51). Lung cancer risk increased with duration of occupational exposure (SMR 2.80, 2.99, and 5.02 for 14, 15-29, and 30 years of employment, respectively). Lung cancer risk was higher for the silicotics without tuberculosis (SMR 3.72) than for those with tuberculosis (SMR 2.83). Indirect adjustment for smoking habits, including number of cigarettes smoked per day, showed that smoking would have been responsible for a maximum risk of 1.77. Thus smoking may have explained 50% of the observed excess mortality from lung cancer.
KW - Epidemiology
KW - Italian silicotics
KW - Pulmonary tuberculosis
KW - Respiratory tract cancer
KW - Smoking
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UR - http://www.scopus.com/inward/citedby.url?scp=0029616121&partnerID=8YFLogxK
M3 - Article
C2 - 8929697
AN - SCOPUS:0029616121
VL - 21
SP - 77
EP - 80
JO - Scandinavian Journal of Work, Environment and Health
JF - Scandinavian Journal of Work, Environment and Health
SN - 0355-3140
IS - SUPPL. 2
ER -