Mortality in an area contaminated by TCDD following an industrial incident

P. A. Bertazzi, C. Zocchetti, A. C. Pesatori, S. Guercilena, M. Sanarico, L. Radice

Research output: Contribution to journalArticlepeer-review


The mortality experience of the population, aged 20-74 years, living in an area contaminated by TCDD after an industrial accident in 1976, was examined in the period 1976-1986 and compared with the mortality of the population of the surrounding noncontaminated territory. People who left the area during the study period were followed up, and vital status was successfully ascertained for over 99% of the cohort members. An increased mortality, from chronic ischemic heart disease (males) and hypertensive disease (females), which could not be explained in terms of chance, confounding, of bias, was noted in the exposed population. The stressful experience of the population in the aftermath of the disaster was deemed relevant to the interpretation of these findings. Overall, cancer mortality was not increased. Suggestive increases, however, were seen for melanoma, brain cancer, soft tissue sarcomas and certain hematologic neoplasms, wheras mortality from breast cancer and cancer of the liver was noticeably decreased. Further research is in progress in order to thoroughly investigate the association, if any, of cancer occurrence with TCDD contamination.

Original languageEnglish
Pages (from-to)316-329
Number of pages14
JournalMedicina del Lavoro
Issue number4
Publication statusPublished - 1989

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health


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