Morvan chorea and agrypnia excitata: When video-polysomnographic recording guides the diagnosis

Federica Provini, Sara Marconi, Marcello Amadori, Pietro Guaraldi, Giulia Pierangeli, Pietro Cortelli, Elio Lugaresi, Pasquale Montagna, Paolo Tinuper

Research output: Contribution to journalArticlepeer-review


Introduction: Morvan chorea is an antibody-mediated limbic encephalopathy characterized by severe insomnia, mental confusion, hallucinations, enacted dreams, hyperhidrosis, and neuromyotonia. Case description: In a 78. years old man presenting with progressive insomnia apathy and depression, a video-polysomnogram documented enacted dreams mimicking daily life activity (oneiric stupor). This finding led us to perform a search for serum antibodies to voltage-gated K+ channels, which was positive. A diagnosis of Morvan chorea was done. The patient underwent plasma exchange with complete resolution of the clinical picture. Conclusions: Oneiric stupor may represent a useful precocious diagnostic marker in Morvan chorea.

Original languageEnglish
Pages (from-to)1041-1043
Number of pages3
JournalSleep Medicine
Issue number10
Publication statusPublished - Dec 2011


  • Agrypnia excitata
  • Limbic encephalopathy
  • Morvan chorea
  • Oneiric stupor
  • REM sleep behaviour disorder
  • Video-polysomnography

ASJC Scopus subject areas

  • Medicine(all)


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