Mother and daughter carrying the same KCNJ11 mutation but with a different response to switching from insulin to sulfonylurea

Chiara Russo, Alessandro Salina, Concetta Aloi, Dario Iafusco, Renata Lorini, Giuseppe d'Annunzio

Research output: Contribution to journalArticlepeer-review

Abstract

KCNJ11 gene mutations are related to permanent neonatal diabetes mellitus (PNDM). Glycemic stability minimizes the risk of complications. Sulfonylureas (SU) are the proven best therapeutic option. We report a 18-month follow-up of switching from insulin to SU in a mother and her daughter with PNDM due to KCNJ11 mutation.

Original languageEnglish
JournalDiabetes Research and Clinical Practice
Volume94
Issue number2
DOIs
Publication statusPublished - Nov 2011

Keywords

  • KCNJ11
  • PNDM treatment
  • Sulfonylureas
  • Switch to SU

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Internal Medicine
  • Endocrinology

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