KCNJ11 gene mutations are related to permanent neonatal diabetes mellitus (PNDM). Glycemic stability minimizes the risk of complications. Sulfonylureas (SU) are the proven best therapeutic option. We report a 18-month follow-up of switching from insulin to SU in a mother and her daughter with PNDM due to KCNJ11 mutation.
- PNDM treatment
- Switch to SU
ASJC Scopus subject areas
- Endocrinology, Diabetes and Metabolism
- Internal Medicine