Mother and daughter carrying the same KCNJ11 mutation but with a different response to switching from insulin to sulfonylurea

Chiara Russo; Alessandro Salina; Concetta Aloi; Dario Iafusco; Renata Lorini; Giuseppe d'Annunzio

doi:10.1016/j.diabres.2011.07.039

Mother and daughter carrying the same KCNJ11 mutation but with a different response to switching from insulin to sulfonylurea

Chiara Russo, Alessandro Salina, Concetta Aloi, Dario Iafusco, Renata Lorini, Giuseppe d'Annunzio

Istituto "Giannina Gaslini"

Research output: Contribution to journal › Article › peer-review

Abstract

KCNJ11 gene mutations are related to permanent neonatal diabetes mellitus (PNDM). Glycemic stability minimizes the risk of complications. Sulfonylureas (SU) are the proven best therapeutic option. We report a 18-month follow-up of switching from insulin to SU in a mother and her daughter with PNDM due to KCNJ11 mutation.

Original language	English
Journal	Diabetes Research and Clinical Practice
Volume	94
Issue number	2
DOIs	https://doi.org/10.1016/j.diabres.2011.07.039
Publication status	Published - Nov 2011

Keywords

KCNJ11
PNDM treatment
Sulfonylureas
Switch to SU

ASJC Scopus subject areas

Endocrinology, Diabetes and Metabolism
Internal Medicine
Endocrinology

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10.1016/j.diabres.2011.07.039

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Mother and daughter carrying the same KCNJ11 mutation but with a different response to switching from insulin to sulfonylurea. / Russo, Chiara; Salina, Alessandro; Aloi, Concetta; Iafusco, Dario; Lorini, Renata; d'Annunzio, Giuseppe.

In: Diabetes Research and Clinical Practice, Vol. 94, No. 2, 11.2011.

Research output: Contribution to journal › Article › peer-review

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AU - Lorini, Renata

AU - d'Annunzio, Giuseppe

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Mother and daughter carrying the same KCNJ11 mutation but with a different response to switching from insulin to sulfonylurea

Abstract

Keywords

ASJC Scopus subject areas

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