Mother and daughter carrying the same KCNJ11 mutation but with a different response to switching from insulin to sulfonylurea

Chiara Russo, Alessandro Salina, Concetta Aloi, Dario Iafusco, Renata Lorini, Giuseppe d'Annunzio

Research output: Contribution to journalArticle

Abstract

KCNJ11 gene mutations are related to permanent neonatal diabetes mellitus (PNDM). Glycemic stability minimizes the risk of complications. Sulfonylureas (SU) are the proven best therapeutic option. We report a 18-month follow-up of switching from insulin to SU in a mother and her daughter with PNDM due to KCNJ11 mutation.

Original languageEnglish
JournalDiabetes Research and Clinical Practice
Volume94
Issue number2
DOIs
Publication statusPublished - Nov 2011

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Keywords

  • KCNJ11
  • PNDM treatment
  • Sulfonylureas
  • Switch to SU

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Internal Medicine
  • Endocrinology

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