Mother and daughter carrying the same KCNJ11 mutation but with a different response to switching from insulin to sulfonylurea

Chiara Russo; Alessandro Salina; Concetta Aloi; Dario Iafusco; Renata Lorini; Giuseppe d'Annunzio

doi:10.1016/j.diabres.2011.07.039

Mother and daughter carrying the same KCNJ11 mutation but with a different response to switching from insulin to sulfonylurea

Chiara Russo, Alessandro Salina, Concetta Aloi, Dario Iafusco, Renata Lorini, Giuseppe d'Annunzio

Istituto "Giannina Gaslini"

Research output: Contribution to journal › Article

Abstract

KCNJ11 gene mutations are related to permanent neonatal diabetes mellitus (PNDM). Glycemic stability minimizes the risk of complications. Sulfonylureas (SU) are the proven best therapeutic option. We report a 18-month follow-up of switching from insulin to SU in a mother and her daughter with PNDM due to KCNJ11 mutation.

Original language	English
Journal	Diabetes Research and Clinical Practice
Volume	94
Issue number	2
DOIs	https://doi.org/10.1016/j.diabres.2011.07.039
Publication status	Published - Nov 2011

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Keywords

KCNJ11
PNDM treatment
Sulfonylureas
Switch to SU

ASJC Scopus subject areas

Endocrinology, Diabetes and Metabolism
Internal Medicine
Endocrinology

Cite this

Russo, C., Salina, A., Aloi, C., Iafusco, D., Lorini, R., & d'Annunzio, G. (2011). Mother and daughter carrying the same KCNJ11 mutation but with a different response to switching from insulin to sulfonylurea. Diabetes Research and Clinical Practice, 94(2). https://doi.org/10.1016/j.diabres.2011.07.039

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Access to Document

10.1016/j.diabres.2011.07.039