Motor cortex changes in spinal cord injury: A TMS study

Eleonora Saturno, Claudio Bonato, Carlo Miniussi, Vincenzodi Lazzaro, Leonardo Callea

Research output: Contribution to journalArticle

Abstract

Using paired pulse transcranial magnetic stimulation (TMS) paradigms, we studied cortical excitability in a patient with spinal cord lesion. During posterior tibial nerve stimulation, the contextual flexion of hand fingers contralateral to the stimulated lower limb had suggested a change in motor cortex excitability. Results showed a decrease in the activity of motor cortex inhibitory circuits. This could suggest that in spinal cord injury, just as in stroke and peripheral deafferentation, a disinhibition of latent synapses within the motor cortex and the rewriting of a new motor map can occur.

Original languageEnglish
Pages (from-to)1084-1085
Number of pages2
JournalNeurological Research
Volume30
Issue number10
DOIs
Publication statusPublished - Dec 2008

Keywords

  • Motor cortex plasticity
  • Spinal cord lesion
  • TMS

ASJC Scopus subject areas

  • Clinical Neurology
  • Neurology

Fingerprint Dive into the research topics of 'Motor cortex changes in spinal cord injury: A TMS study'. Together they form a unique fingerprint.

  • Cite this

    Saturno, E., Bonato, C., Miniussi, C., Lazzaro, V., & Callea, L. (2008). Motor cortex changes in spinal cord injury: A TMS study. Neurological Research, 30(10), 1084-1085. https://doi.org/10.1179/174313208X332968