Motor cortex changes in spinal cord injury

A TMS study

Eleonora Saturno, Claudio Bonato, Carlo Miniussi, Vincenzodi Lazzaro, Leonardo Callea

Research output: Contribution to journalArticle

24 Citations (Scopus)

Abstract

Using paired pulse transcranial magnetic stimulation (TMS) paradigms, we studied cortical excitability in a patient with spinal cord lesion. During posterior tibial nerve stimulation, the contextual flexion of hand fingers contralateral to the stimulated lower limb had suggested a change in motor cortex excitability. Results showed a decrease in the activity of motor cortex inhibitory circuits. This could suggest that in spinal cord injury, just as in stroke and peripheral deafferentation, a disinhibition of latent synapses within the motor cortex and the rewriting of a new motor map can occur.

Original languageEnglish
Pages (from-to)1084-1085
Number of pages2
JournalNeurological Research
Volume30
Issue number10
DOIs
Publication statusPublished - Dec 2008

Fingerprint

Transcranial Magnetic Stimulation
Motor Cortex
Spinal Cord Injuries
Tibial Nerve
Synapses
Fingers
Lower Extremity
Spinal Cord
Hand
Stroke

Keywords

  • Motor cortex plasticity
  • Spinal cord lesion
  • TMS

ASJC Scopus subject areas

  • Clinical Neurology
  • Neurology

Cite this

Saturno, E., Bonato, C., Miniussi, C., Lazzaro, V., & Callea, L. (2008). Motor cortex changes in spinal cord injury: A TMS study. Neurological Research, 30(10), 1084-1085. https://doi.org/10.1179/174313208X332968

Motor cortex changes in spinal cord injury : A TMS study. / Saturno, Eleonora; Bonato, Claudio; Miniussi, Carlo; Lazzaro, Vincenzodi; Callea, Leonardo.

In: Neurological Research, Vol. 30, No. 10, 12.2008, p. 1084-1085.

Research output: Contribution to journalArticle

Saturno, E, Bonato, C, Miniussi, C, Lazzaro, V & Callea, L 2008, 'Motor cortex changes in spinal cord injury: A TMS study', Neurological Research, vol. 30, no. 10, pp. 1084-1085. https://doi.org/10.1179/174313208X332968
Saturno E, Bonato C, Miniussi C, Lazzaro V, Callea L. Motor cortex changes in spinal cord injury: A TMS study. Neurological Research. 2008 Dec;30(10):1084-1085. https://doi.org/10.1179/174313208X332968
Saturno, Eleonora ; Bonato, Claudio ; Miniussi, Carlo ; Lazzaro, Vincenzodi ; Callea, Leonardo. / Motor cortex changes in spinal cord injury : A TMS study. In: Neurological Research. 2008 ; Vol. 30, No. 10. pp. 1084-1085.
@article{d857f6e2b5a64917ba3c0cc519fe9be3,
title = "Motor cortex changes in spinal cord injury: A TMS study",
abstract = "Using paired pulse transcranial magnetic stimulation (TMS) paradigms, we studied cortical excitability in a patient with spinal cord lesion. During posterior tibial nerve stimulation, the contextual flexion of hand fingers contralateral to the stimulated lower limb had suggested a change in motor cortex excitability. Results showed a decrease in the activity of motor cortex inhibitory circuits. This could suggest that in spinal cord injury, just as in stroke and peripheral deafferentation, a disinhibition of latent synapses within the motor cortex and the rewriting of a new motor map can occur.",
keywords = "Motor cortex plasticity, Spinal cord lesion, TMS",
author = "Eleonora Saturno and Claudio Bonato and Carlo Miniussi and Vincenzodi Lazzaro and Leonardo Callea",
year = "2008",
month = "12",
doi = "10.1179/174313208X332968",
language = "English",
volume = "30",
pages = "1084--1085",
journal = "Neurological Research",
issn = "0161-6412",
publisher = "Maney Publishing",
number = "10",

}

TY - JOUR

T1 - Motor cortex changes in spinal cord injury

T2 - A TMS study

AU - Saturno, Eleonora

AU - Bonato, Claudio

AU - Miniussi, Carlo

AU - Lazzaro, Vincenzodi

AU - Callea, Leonardo

PY - 2008/12

Y1 - 2008/12

N2 - Using paired pulse transcranial magnetic stimulation (TMS) paradigms, we studied cortical excitability in a patient with spinal cord lesion. During posterior tibial nerve stimulation, the contextual flexion of hand fingers contralateral to the stimulated lower limb had suggested a change in motor cortex excitability. Results showed a decrease in the activity of motor cortex inhibitory circuits. This could suggest that in spinal cord injury, just as in stroke and peripheral deafferentation, a disinhibition of latent synapses within the motor cortex and the rewriting of a new motor map can occur.

AB - Using paired pulse transcranial magnetic stimulation (TMS) paradigms, we studied cortical excitability in a patient with spinal cord lesion. During posterior tibial nerve stimulation, the contextual flexion of hand fingers contralateral to the stimulated lower limb had suggested a change in motor cortex excitability. Results showed a decrease in the activity of motor cortex inhibitory circuits. This could suggest that in spinal cord injury, just as in stroke and peripheral deafferentation, a disinhibition of latent synapses within the motor cortex and the rewriting of a new motor map can occur.

KW - Motor cortex plasticity

KW - Spinal cord lesion

KW - TMS

UR - http://www.scopus.com/inward/record.url?scp=57449101679&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=57449101679&partnerID=8YFLogxK

U2 - 10.1179/174313208X332968

DO - 10.1179/174313208X332968

M3 - Article

VL - 30

SP - 1084

EP - 1085

JO - Neurological Research

JF - Neurological Research

SN - 0161-6412

IS - 10

ER -