MouBeAT: A new and open toolbox for guided analysis of behavioral tests in mice

E Bello-Arroyo, H Roque, A Marcos, J Orihuel, A Higuera-Matas, M Desco, VR Caiolfa, E Ambrosio, E Lara-Pezzi, MV Gómez-Gaviro

Research output: Contribution to journalArticle

Abstract

Animal behavioral tests are essential to understand the bases of neurologic and psychological disorders, which can be evaluated by different methodological and experimental models. However, the quantification of behavioral tests results is limited by the considerable amount of time needed for manual evaluation and the high costs of automated analysis software. To overcome these limitations, we describe here a new, open source toolbox for ImageJ, called Mouse Behavioral Analysis Toolbox (MouBeAT), designed to analyze different behavioral tests in rodents semi-automatically. These tests include Open Field (OF), Elevated Plus Maze (EPM), Y-maze (YM) test and Morris Water Maze (MWM). MouBeAT showed a high correlation with manual evaluation in all the parameters analyzed for all the behavioral tests, reinforcing its value as an accurate analysis tool. This new tool is freely available online. © 2018 Bello-Arroyo, Roque, Marcos, Orihuel, Higuera-Matas, Desco, Caiolfa, Ambrosio, Lara-Pezzi and Gómez-Gaviro.
Original languageEnglish
Article number201
JournalFrontiers in Behavioral Neuroscience
Volume12
DOIs
Publication statusPublished - 2018

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Nervous System Diseases
Rodentia
Theoretical Models
Software
Psychology
Costs and Cost Analysis
Behavior Rating Scale
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Bello-Arroyo, E., Roque, H., Marcos, A., Orihuel, J., Higuera-Matas, A., Desco, M., ... Gómez-Gaviro, MV. (2018). MouBeAT: A new and open toolbox for guided analysis of behavioral tests in mice. Frontiers in Behavioral Neuroscience, 12, [201]. https://doi.org/10.3389/fnbeh.2018.00201

MouBeAT: A new and open toolbox for guided analysis of behavioral tests in mice. / Bello-Arroyo, E; Roque, H; Marcos, A; Orihuel, J; Higuera-Matas, A; Desco, M; Caiolfa, VR; Ambrosio, E; Lara-Pezzi, E; Gómez-Gaviro, MV.

In: Frontiers in Behavioral Neuroscience, Vol. 12, 201, 2018.

Research output: Contribution to journalArticle

Bello-Arroyo, E, Roque, H, Marcos, A, Orihuel, J, Higuera-Matas, A, Desco, M, Caiolfa, VR, Ambrosio, E, Lara-Pezzi, E & Gómez-Gaviro, MV 2018, 'MouBeAT: A new and open toolbox for guided analysis of behavioral tests in mice', Frontiers in Behavioral Neuroscience, vol. 12, 201. https://doi.org/10.3389/fnbeh.2018.00201
Bello-Arroyo, E ; Roque, H ; Marcos, A ; Orihuel, J ; Higuera-Matas, A ; Desco, M ; Caiolfa, VR ; Ambrosio, E ; Lara-Pezzi, E ; Gómez-Gaviro, MV. / MouBeAT: A new and open toolbox for guided analysis of behavioral tests in mice. In: Frontiers in Behavioral Neuroscience. 2018 ; Vol. 12.
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