Abstract
This article focuses on the potential therapeutic uses of transcranial magnetic stimulation (TMS) in movement disorders. The brain can be stimulated with low levels of direct electrical current, called direct current polarization (tDCS). High-frequency repetitive TMS might increase brain excitability and be used for therapy in Parkinson's disease. Single sessions with TMS, however, have not proven to be very effective. Treatment with tDCS has been performed in some open studies with some success, but these results need confirmation. Physiological findings in dystonia reveal a decrease in intracortical inhibition. There have been a few studies of patients with Tourette's syndrome with mixed results. To date, clinical results with TMS in movement disorders have been mixed, and more work will be needed to clarify the potential clinical role of TMS.
| Original language | English |
|---|---|
| Title of host publication | Oxford Handbook of Transcranial Stimulation |
| Publisher | Oxford University Press |
| ISBN (Print) | 9780191744013, 9780198568926 |
| DOIs | |
| Publication status | Published - Nov 21 2012 |
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Keywords
- Brain excitability
- Direct current polarization
- Dystonia
- Movement disorders
- Parkinson's disease
- Therapy
ASJC Scopus subject areas
- Psychology(all)
Cite this
Movement Disorders. / Hallett, Mark; Berardelli, Alfredo.
Oxford Handbook of Transcranial Stimulation. Oxford University Press, 2012.Research output: Chapter in Book/Report/Conference proceeding › Chapter
}
TY - CHAP
T1 - Movement Disorders
AU - Hallett, Mark
AU - Berardelli, Alfredo
PY - 2012/11/21
Y1 - 2012/11/21
N2 - This article focuses on the potential therapeutic uses of transcranial magnetic stimulation (TMS) in movement disorders. The brain can be stimulated with low levels of direct electrical current, called direct current polarization (tDCS). High-frequency repetitive TMS might increase brain excitability and be used for therapy in Parkinson's disease. Single sessions with TMS, however, have not proven to be very effective. Treatment with tDCS has been performed in some open studies with some success, but these results need confirmation. Physiological findings in dystonia reveal a decrease in intracortical inhibition. There have been a few studies of patients with Tourette's syndrome with mixed results. To date, clinical results with TMS in movement disorders have been mixed, and more work will be needed to clarify the potential clinical role of TMS.
AB - This article focuses on the potential therapeutic uses of transcranial magnetic stimulation (TMS) in movement disorders. The brain can be stimulated with low levels of direct electrical current, called direct current polarization (tDCS). High-frequency repetitive TMS might increase brain excitability and be used for therapy in Parkinson's disease. Single sessions with TMS, however, have not proven to be very effective. Treatment with tDCS has been performed in some open studies with some success, but these results need confirmation. Physiological findings in dystonia reveal a decrease in intracortical inhibition. There have been a few studies of patients with Tourette's syndrome with mixed results. To date, clinical results with TMS in movement disorders have been mixed, and more work will be needed to clarify the potential clinical role of TMS.
KW - Brain excitability
KW - Direct current polarization
KW - Dystonia
KW - Movement disorders
KW - Parkinson's disease
KW - Therapy
UR - http://www.scopus.com/inward/record.url?scp=84923674101&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84923674101&partnerID=8YFLogxK
U2 - 10.1093/oxfordhb/9780198568926.013.0044
DO - 10.1093/oxfordhb/9780198568926.013.0044
M3 - Chapter
AN - SCOPUS:84923674101
SN - 9780191744013
SN - 9780198568926
BT - Oxford Handbook of Transcranial Stimulation
PB - Oxford University Press
ER -